A multi-targeted approach to suppress tumor-promoting inflammationBroad targeting of angiogenesis for cancer prevention and therapyBroad targeting of resistance to apoptosis in cancer.Cancer prevention and therapy through the modulation of the tumor microenvironmentDesigning a broad-spectrum integrative approach for cancer prevention and treatment.Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Immune evasion in cancer: Mechanistic basis and therapeutic strategies.Progeroid syndromes: models for stem cell aging?Seeding drug discovery: integrating telomerase cancer biology and cellular senescence to uncover new therapeutic opportunities in targeting cancer stem cells.Stem cell ageing: does it happen and can we intervene?Sustained proliferation in cancer: Mechanisms and novel therapeutic targetsTargeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.Therapeutic targeting of replicative immortalityTissue invasion and metastasis: Molecular, biological and clinical perspectives
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