coumarin 7-hydroxylase activityarachidonic acid monooxygenase activitysteroid hydroxylase activitynaphthalene hydroxylase activityretinoic acid 4-hydroxylase activity2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activitycarotene beta-ring hydroxylase activityoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygenoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygennitrilotriacetate monooxygenase activitymethyl tertiary butyl ether 3-monooxygenase activity4-nitrocatechol 4-monooxygenase activity4-chlorophenoxyacetate monooxygenase activitytert-butanol 2-monooxygenase activityalpha-pinene monooxygenase activityammonia monooxygenase activity2-hydroxyisobutyrate 3-monooxygenase activitydibenzothiophene-5,5-dioxide monooxygenase activity4-methoxybenzoate monooxygenase (O-demethylating) activitydeoxyhypusine monooxygenase activityornithine N5-monooxygenase activityluciferin monooxygenase activityp-coumarate 3-hydroxylase activityferulate 5-hydroxylase activityandrost-4-ene-3,17-dione monooxygenase activityphylloquinone monooxygenase (2,3-epoxidizing) activity2-hydroxypyridine 5-monooxygenase activity3-hydroxybenzoate 2-monooxygenase activityestradiol 6-beta-monooxygenase activitylinalool 8-monooxygenase activityprogesterone 11-alpha-monooxygenase activityprogesterone monooxygenase activitysteroid 9-alpha-monooxygenase activitythiophene-2-carbonyl-CoA monooxygenase activityechinenone 3-hydroxylase activity
subClassOf
Defective CYP1B1 does not 4-hydroxylate EST17bCYP2C8 inactivates paclitaxel by 6alpha-hydroxylationCYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHACYP4F3 20-hydroxylates LTB4N-atom dealkylation of caffeineDefective CYP4F22 does not 20-hydroxylate TrXA3CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHADehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromideMEOS oxidizes ethanol to acetaldehydeArachidonic acid is hydroxylated to 20-HETE by CYP(3)CYP1A2, 3A4 oxidise AFB1 to AFNBOO-atom dealkylation of dextromethorphanCYP monooxygenates EPA to 18(S)-HpEPECYP2C19 5-hydroxylates omeprazoleCYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBOTyrosinase oxidises tyrosine to dopaquinoneCYP3A4 can N-demethylate loperamideCYP4F8 19-hydroxylates PGH2N-hydroxylation of 4-aminobiphenylCYP2A13 oxidises AFM1 to AFM1EBenzene is hydroxylated to phenolCYP4F22 20-hydroxylates TrXA3CYP4A11 12-hydroxylates DDCX5ce7802e56914f0abe1b67b300d25ebbDefective CYP2U1 does not omega-hydroxylate ARACYP1A2 S-demethylates 6MMPArachidonic acid is hydroxylated to 19-HETE by CYP(2)CYP4F11 16-hydroxylates 3OH-PALMCyclophosphamide is 4-hydroxylated by CYP2B6DHI and DHICA polymerise forming eumelaninCYP3A4,5 hydroxylates AFB1 to AFQ1Vinyl chloride is oxidized to 2-Chloroethylene oxideFMO2:FAD:Mg2+ S-oxidises MTZCPY4 -oxidises 14(S)-HDHA to MaR-L1CYP1B1 4-hydroxylates EST17bCYP2C18 initiates bioactivation of phenytoin by 4-hydroxylationCYP4 -oxidises 14(R)-HDHA to MaR-L2CYPs hydroxylate DHA to 14(R)-HDHACYP2F1 dehydrogenates 3-methylindoleCYP2C9 inactivates tolbutamide by 4methyl-hydroxylation
annotatedSource
definition
Catalysis of the incorporation ...... other atom of oxygen to water.
database_cross_reference
Reactome:R-HSA-143468
Reactome:R-HSA-156526
Reactome:R-HSA-211882
Reactome:R-HSA-211904
Reactome:R-HSA-211910
Reactome:R-HSA-211919
Reactome:R-HSA-211924
Reactome:R-HSA-211929
Reactome:R-HSA-211948
Reactome:R-HSA-211951
has_obo_namespace
molecular_function
has_related_synonym
hydroxylase activity
id
GO:0004497
in_subset
type
label
monooxygenase activity