single-stranded DNA endodeoxyribonuclease activityexcinuclease ABC activityrestriction endodeoxyribonuclease activityendodeoxyribonuclease activity, producing 5'-phosphomonoestersendodeoxyribonuclease activity, producing 3'-phosphomonoesterssite-specific endodeoxyribonuclease activity, specific for altered baseT/G mismatch-specific endonuclease activityretroviral 3' processing activityflap endonuclease activitydouble-stranded DNA endodeoxyribonuclease activity
subClassOf
283570d69e24b8bd731b61e674873981ERCC1:XPF cleaves flaps generated by SSA5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER3' incision by ERCC5 (XPG) in TC-NERInitial resection of double-strand break ends9db43abb500d8cf8b6ddd00e16239fb63'-incision of DNA by ERCC5 (XPG) in GG-NERMRN:CtIP endonucleolytically cleaves single-strand DNA 3' to SPO11MRN and RBBP8 resect DNA DSBs in MMEJAPEX1 mediates endonucleolytic cleavage at the 5' side of the AP siteMUS81:EME1,EME2 cleaves D-loopCleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)
annotatedSource
definition
Catalysis of the hydrolysis of ...... d by creating internal breaks.
database_cross_reference
Reactome:R-HSA-110359
Reactome:R-HSA-5686440
Reactome:R-HSA-5686657
Reactome:R-HSA-5687464
Reactome:R-HSA-5690988
Reactome:R-HSA-5693584
Reactome:R-HSA-5693608
Reactome:R-HSA-6782204
Reactome:R-HSA-6782224
Reactome:R-HSA-9023941
has_obo_namespace
molecular_function
has_related_synonym
DNA nicking activity
endonuclease G activity
id
GO:0004520
type
label
endodeoxyribonuclease activity