APOA1Apolipoprotein_A1Apolipoprotein_A1Apolipoprot%C3%A9ine_A1Apolipoprote%C3%ADna_A1Apolipoprotein_A1Apolipoproteina_A-IApolipoprote%C3%ADna_A1%D0%90%D0%BF%D0%BE%D0%BB%D0%B8%D0%BF%D0%BE%D0%BF%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD_A1%D0%90%D0%BF%D0%BE%D0%BB%D1%96%D0%BF%D0%BE%D0%BF%D1%80%D0%BE%D1%82%D0%B5%D1%97%D0%BD_A1Q1316030%E8%BD%BD%E8%84%82%E8%9B%8B%E7%99%BDA1
about
sameAs
HPR:APOL1:APOA1:HDL3Ligands of MSR1spherical HDLspherical HDL [endocytic vesicle lumen]Platelet releasate secretory granule proteinsPlatelet releasate secretory granule proteins [extracellular region]nascent CMnascent CM:atREs [extracellular region]mature CM:atREsCRCR [early endosome]FAM20C substratesFAM20C productsABCA7-1:ApoA1 complexnascent chylomicronnascent chylomicron [extracellular region]chylomicron4xPALM-C-p-2S-ABCA1 tetramer:APOA1discoidal HDLpre-beta HDLTG-depleted chylomicronspherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-IIIenlarged spherical HDLspherical HDL [plasma membrane]apoA-I:CUBN:AMN complexExpression of APOA1ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicronBMP1-3:Zn2+ cleaves pro-APOA1 to APOA14xPALM-C-p-2S-ABCA1 tetramer binds APOA1Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particlecholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)apoA-I binds to CUBN:AMN
P527
P688
Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genesApolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptakeApolipoprotein specificity for lipid efflux by the human ABCAI transporterApolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicityUptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier modelApolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanismsCharacterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoproteinDistribution and localization of lecithin:cholesterol acyltransferase and cholesteryl ester transfer activity in A-I-containing lipoproteinsBinding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1Scavenger receptor SR-BI in macrophage lipid metabolismA protein cofactor of lecithin:cholesterol acyltransferaseInteraction of rat lecithin-cholesterol acyltransferase with rat apolipoprotein A-I and with lecithin-cholesterol vesiclesThe apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteinsApolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporterSterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolismABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-IScavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structureApoprotein (E--A-II) complex of human plasma lipoproteins. I. Characterization of this mixed disulfide and its identification in a high density lipoprotein subfractionStructure and interfacial properties of human apolipoprotein A-VABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cellsA novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery diseaseThe ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier diseaseApolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activityHemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoproteinEnhanced cholesterol efflux by tyrosyl radical-oxidized high density lipoprotein is mediated by apolipoprotein AI-AII heterodimersThe extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrilsStructural and functional properties of human and mouse apolipoprotein A-IRole of apolipoprotein A-I in the structure of human serum high density lipoproteins. Reconstitution studiesThe role of different regions of ATP-binding cassette transporter A1 in cholesterol effluxApolipoproteins A-I and A-II downregulate neutrophil functionsReconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesteraseProteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOFIdentification of an amyloid fibril forming peptide comprising residues 46-59 of apolipoprotein A-IIsolation and characterization of human apolipoprotein M-containing lipoproteinsAmyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing - a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosisHelical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7Association of human, rat, and rabbit apolipoprotein E with beta-amyloidHeat shock protein 60 is a high-affinity high-density lipoprotein binding proteinMethionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I.Novel N-terminal mutation of human apolipoprotein A-I reduces self-association and impairs LCAT activation
P921
Q50177632-7818AF12-60B0-4AB0-B042-D568C6867629Q50177694-384A32BD-9855-46F5-8AF3-7C7CB8E23C73Q50177800-B6F47F39-9308-45C0-8D3D-5E99CB219AA8Q50181526-27A3B34B-8ED2-488A-ADCF-5DDB95125C95Q50259242-CB0E57E2-AD76-4EFA-9A97-F1C89C601EBAQ50259243-D51EFD9F-54A1-4EF0-AE7E-8B77FAF02DF4Q50266453-07CEA062-259C-4879-B7E4-A90CBD0A2C2CQ50266460-D3D8D532-167A-44DB-A159-776604787DB3Q50266470-8C57676F-0CBD-4086-8111-3B0D0FC4A59BQ50266475-2CC3EADB-2321-4026-856D-0910022FD449Q50266487-F704C738-A791-41D5-8DAF-C62BFA613F45Q50269397-1EED29E1-7099-4B65-8FF6-6F18878C8C81Q50269401-A27A5B86-AF65-4C12-81A1-99BA6CA449B3Q50274379-EABE01BF-5EF0-4AF6-A960-101A31F1FAEDQ50274712-760EFA0A-566C-4E50-82D7-246370560802Q50274713-3BD4CE0E-AE7B-453A-B056-B201650D38C7Q50274715-BCB098A1-70F7-4947-A657-C20806102F44Q50274726-78FB81A6-EDAE-479C-A01B-64A7E24B1EE0Q50274727-C1959B61-2702-47F5-AF83-4546FD5C5BA0Q50274728-8F256F3E-803D-4CA9-8E7C-9088D2EC0187Q50274739-BB6B28EB-71C0-437F-8923-2BBD47DEAC87Q50274740-B997D775-4E8F-4DD9-81E5-E0406CDF4C20Q50274750-B54C0C67-DA35-49EC-B478-7C00C77DA8F2Q50274801-B2870378-01F1-4A2A-AFD3-02AA55893157Q50274803-231A2ED9-4192-46FB-BAC3-E295243ECBF2Q50293428-FE455925-0BFB-419F-BE3F-98163B2D7C0DQ50299720-C761961D-E4E9-44FE-9437-0F92B0A2E855Q50299729-DABAD2CB-3CAF-4429-8583-F104DADC5EE3Q50299729-EEF40ECC-FA0D-4CF1-A1F6-0B5804DA53FCQ50299734-E56C30C0-DA4D-4E80-BA42-2B0E940A784CQ50299738-152C6A7D-B060-4D19-AE6F-09E7B7E79EE6Q50299767-BFAE6C56-0CF8-46E8-B47E-B69B834DB5C0Q50299806-90BBF4D8-E9BA-4A86-A155-0586F1FB07B7
P527
Q22010789-7D6186E0-5672-4EEA-99F7-430F9979C28BQ22253883-A8619E76-F7B8-4930-9DBF-4CF9EC7C3EA4Q24290771-0C49408C-C843-4A66-9341-661B4962CCA0Q24291110-AC990E28-1E0D-4937-982B-7E8F58047BFEQ24292859-1717AA5F-DA16-4AE5-87F9-9E2C1EC748F1Q24294266-F9F7800A-0C36-4AC2-8275-7DCC192DE678Q24294419-9FE07450-FEAF-4646-B1B8-9B31F09EC0E0Q24296368-94C33008-376F-4AF1-80AB-638150EECC18Q24298291-204C56E2-76B7-4019-A247-B40DE55694B7Q24299462-05E8E89F-CF90-484A-BFBE-9CDC43B7C321Q24300472-0012FD44-9CD7-48AC-AC60-6DC51C1F10CAQ24301489-791E15A7-7A01-441A-B8B9-0C3ED67E7ED2Q24302322-1427641E-371A-4647-ABAE-029488ADD648Q24302387-3AF72206-A7E3-4929-AF1A-FEB3A857209EQ24303527-EBF11C02-81B2-4BC9-9BED-DF4A197069C4Q24303897-FE885C64-370D-4BE6-A7E6-C4001B5383AEQ24304399-1E964C1B-B33C-406A-8DE9-AD03D1E7EBBAQ24304498-BBBD3D5C-3ED1-4108-A4D6-DE49C37303DAQ24305368-8DB19863-C16A-4FFA-B67C-536382BB5777Q24305511-646DBBCF-A54C-41D2-9929-6830F1B7C1BFQ24306084-D77C9B5B-817A-4330-B2C7-C1A646F58623Q24306475-DF5B6DC6-D0E0-4D64-8B19-18AF8394BD42Q24309114-1ABC03E4-C219-4D09-94D5-99F75B718CBEQ24309793-E9071A0D-35DB-44E2-8C9D-99439C6685A5Q24311407-9F45658F-D5D9-4EA0-B70F-5898F699C83AQ24311701-03E29A0A-B25B-4ADD-83B3-9AB75D46F099Q24315953-C29E972D-1F69-4628-B871-BB66AAE0F18DQ24316294-6AAC4AC5-3C99-4E18-8302-244246E0394AQ24322415-63CEC543-3729-4F59-BF54-2758FE3A9036Q24322583-44DD0CC8-2D55-48B3-9DF0-842C3889425DQ24322715-0F1C1CAB-30F3-472C-8F45-62E06784A87CQ24323213-09A921B8-3EEF-400B-8FE7-B26688AC9D9AQ24323500-B30E4CE8-C40D-4C04-878D-D36627ADF3C1Q24336276-A3AE49A2-8441-4359-9BE4-CC96DDE0249EQ28116206-37274CA1-7602-44EF-AA33-62454D054D5FQ28508207-E351DEED-1935-4C92-AC51-07F5602912AAQ28771374-9413ED9E-60E4-48D7-BB6F-FF2BB6309468Q28910469-47E5A665-CDB2-4681-A4C5-848E81F837ACQ33719586-B0947A03-2D6E-4FC5-8B32-85586DE19D45Q34395097-DDF2CF98-7119-452B-92C1-4631FBC8DBC5
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Apolipoprotein A1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
APOA1
@cy
Apolipoproteiini A-1 Milano
@fi
Apolipoprotein A1
@de
Apolipoprotein A1
@en
Apolipoprotein A1
@fr
Apolipoprotein A1
@hr
Apolipoprotein A1
@nl
Apolipoproteina A-I
@pl
Apolipoproteína A1
@gl
Apolipoproteína A1
@pt
type
label
APOA1
@cy
Apolipoproteiini A-1 Milano
@fi
Apolipoprotein A1
@de
Apolipoprotein A1
@en
Apolipoprotein A1
@fr
Apolipoprotein A1
@hr
Apolipoprotein A1
@nl
Apolipoproteina A-I
@pl
Apolipoproteína A1
@gl
Apolipoproteína A1
@pt
altLabel
APOA1
@en
apo-AI
@en
apolipoprotein A-I
@en
epididymis secretory sperm binding protein
@en
prefLabel
APOA1
@cy
Apolipoproteiini A-1 Milano
@fi
Apolipoprotein A1
@de
Apolipoprotein A1
@en
Apolipoprotein A1
@fr
Apolipoprotein A1
@hr
Apolipoprotein A1
@nl
Apolipoproteina A-I
@pl
Apolipoproteína A1
@gl
Apolipoproteína A1
@pt
P637
P638
P680
P681
P682
P705
P352
P6366
P646
P31
P352
P6366
2780745583
P637
NP_001304946
NP_001304947
NP_001304950
P638
P646
/m/02pr60_
P680
P681
P682
P702
P703
P705
ENSP00000236850
ENSP00000352471
ENSP00000364469
ENSP00000364472
ENSP00000364478