about
P688
Activation of Arp2/3 complex-mediated actin polymerization by cortactinDifferential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) proteinErk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASPCortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusionA Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosisAn essential role for cortactin in the modulation of the potassium channel Kv1.2.Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formationStructure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherinMass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cellsA noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactinDisease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagyClass IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactinF-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammationCortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shapeWAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motilityAbl2/Arg controls dendritic spine and dendrite arbor stability via distinct cytoskeletal control pathwaysCortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturationRegulated interactions between dynamin and the actin-binding protein cortactin modulate cell shapeArg interacts with cortactin to promote adhesion-dependent cell edge protrusionSrc-dependent phosphorylation of ASAP1 regulates podosomes.Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activationCortactin regulates cell migration through activation of N-WASPp120 catenin regulates lamellipodial dynamics and cell adhesion in cooperation with cortactinSrc phosphorylation of cortactin enhances actin assembly.Tyrosine phosphorylation controls cortactin binding to two enterohaemorrhagic Escherichia coli effectors: Tir and EspFu/TccP.
P921
Q24290885-5E685202-531A-4810-A8D2-514B0DE955D8Q24293512-D5283FA9-70C5-4EE9-9056-45F2D28E012DQ24294671-107C1FD0-8073-49FD-BE99-3539D966295EQ24296813-86E93E0D-382E-48DF-A111-F0903F3B1838Q24298217-286BEA54-DB42-4C9D-BF67-6D78FB1AF9E3Q24298623-FDED5D9A-A214-49F9-90D6-D0432BAE5855Q24301359-8F2D19AC-CAAD-44F9-BE50-D176CB85B33EQ24302086-38DE36AA-883E-4293-9A2C-41BD6EAB2DC2Q24303586-85F3032D-A3B2-45CB-9141-3A764F654FBBQ24309321-A900A216-6A3E-44A7-B07C-1188400F7419Q24311582-35C519B2-18E7-4222-90EE-2BCBB17CC9DBQ24322940-D682798C-F984-4193-BF3E-F65C9E0DFE5AQ24337221-27B922AD-1E8C-4F6D-8551-FDAF0D347AF8Q24681508-AED3E53C-566B-425E-9599-36403ECB6EBEQ28200991-377C3C16-621D-4E48-BAF0-342A89F9E5D9Q28507062-11E323F7-82FE-488D-97C1-6323C15588FEQ28508552-66A3D885-8D88-4057-81E8-4F4BD8125968Q28508669-5321B222-B916-4B96-9DCD-34588E73C03EQ28510777-5C16367B-E2CE-4330-8B9F-8804F4BDD1F8Q28585696-B23C2085-28B2-4215-9C1F-76E8E56EE2FEQ28587177-F8B71BE8-C14C-4065-8DEA-1B8071148823Q28591682-FE4758B2-43D5-4EB3-85BA-07EC5056C897Q28594449-92B4B348-2035-46E8-BA7E-DEF250F2DCCCQ30444077-CCE8CEF1-84FD-42D3-8862-3655CAD79D9CQ35901190-2E409AA5-468D-4346-A2EA-441562CD59F2Q40142577-78F575AF-3518-473B-A0F1-8452F5A44CCF
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Cortactin
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Cortactin
@en
type
label
Cortactin
@en
altLabel
Cttn
@en
mammary tumor and squamous cell carcinoma associated (p80/85 src substrate)
@en
src substrate cortactin
@en
uniprot:Q60598
@en
prefLabel
Cortactin
@en
P361
P527
P637
P680
P681
P682
P352
P638
P31
P352
P637
NP_001239501
NP_001344045
P680
P681
P682
P702
P703
P705
ENSMUSP00000033407
ENSMUSP00000099368