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Morpholino antisense oligomers: design, preparation, and propertiesSite-specific DNA photocleavage and photomodulation by oligonucleotide conjugatesOligo/polynucleotide-based gene modification: strategies and therapeutic potentialTransient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomideInhibition of translation of hepatitis C virus RNA by 2-modified antisense oligonucleotidesEffects of antisense oligodeoxynucleotides targeting CCR3 on the airway response to antigen in ratsCD4 expression decrease by antisense oligonucleotides: inhibition of rat T CD4+ cell reactivityStable antisense RNA expression neutralizes the activity of low-density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line.Blockade of connexin 43 expression by stable transfection of antisense cDNA in cultured vascular smooth muscle cells.Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structureSite-directed selection of oligonucleotide antagonists by competitive elution.Cytotoxic hammerhead ribozymes.Detection of proteins binding to short RNA.DNA hybrids or short antisense oligonucleotides in Xenopus laevis oocytes and human macrophage cell extracts by photoaffinity radiolabeling.A method to select chemically modified aptamers directly.Elucidation and characterization of oligonucleotide-accessible sites on HIV-2 leader region RNA.Uptake dynamics and retinal tolerance of phosphorothioate oligonucleotide and its direct delivery into the site of choroidal neovascularization through subretinal administration in the rat.Uptake and quantification of intracellular concentration of lipophilic pro-oligonucleotides in HeLa cells.Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates.Carboranyl oligonucleotides: 4. synthesis and physicochemical studies of oligonucleotides containing 2'-O-(o-carboran-1-yl)methyl group.ROLL: a method of preparation of gene-specific oligonucleotide libraries.Antisense-induced Fas mRNA degradation produces site-specific stable 3'-mRNA fragment by exonuclease cleavage at the complementary sequence.Polyethylenimine but not cationic lipid improves antisense activity of 3'-capped phosphodiester oligonucleotides.Limited use of cationic liposomes as tools to enhance the antiherpetic activities of oligonucleotides in vero cells infected with herpes simplex virus type 1.Conformational preorganization, hydration, and nucleic acid duplex stability.Cellular uptake properties of oligonucleotides in LLC-PK1 renal epithelial cells.Molecular cloning and expression of cDNA for human RNase H.Strategies for generation of an siRNA expression library directed against the human genome.Selection of DNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus and inhibit viral RNA synthesis in vitro.Short pyrimidine stretches containing mixed base PNAs are versatile tools to induce translation elongation arrest and truncated protein synthesis.Analysis of thermal melting curves.2'-Deoxy purine, 2'-O-methyl pyrimidine (dRmY) aptamers as candidate therapeutics.Simultaneous generation of aptamers to multiple gamma-carboxyglutamic acid proteins from a focused aptamer library using DeSELEX and convergent selection.G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells.Benzimidazoles: a minor groove-binding ligand-induced stabilization of triple helix.Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice.Toxicologic effects of an oligodeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats.Mixed backbone oligonucleotides: improvement in oligonucleotide-induced toxicity in vivo.Evaluation of electronic effect of phenyl ring substituents on the DNA minor groove binding properties of novel bis and terbenzimidazoles: synthesis and spectroscopic studies of ligand-DNA interaction.Brain as a unique antisense environment.Suppression of hepatitis C virus genome replication in cells with RNA-cleaving DNA enzymes and short-hairpin RNA.
P1433
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P1433
description
journal
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revista científica
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rivista scientifica
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wetenschappelijk tijdschrift van Mary Ann Liebert, Inc.
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wissenschaftliche Fachzeitschrift
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مجلة
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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Oligonucleotides
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P236
P1055
P1250
P1476
Oligonucleotides
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P236
P3417
Oligonucleotides