about
CoREST complexBHC complexKDM1A;KDM1Bp-T774-PKN1:AR:Androgen:KLK2;KLK3 Gene:Nucleosome with p-T12;Me2K-10-H3:KDM1Ap-T774-PKN1:AR:Androgen:KLK2;KLK3 Gene:Nucleosome with p-T12;MeK-10-H3:KDM1ADemethylase KDM1A binds KLK2 and KLK3 promotersKDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promotersMYC gene; BCL2 gene: H3K9me2; HIST1H2AC nucleosome:ESR1:ESTG:KDM1AKDM1A is recruited to MYC and BCL2 genesKDM1A demethylates H3 on MYC and BCL genes in response to estrogen
P527
P688
Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulationLSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesisHistone demethylation mediated by the nuclear amine oxidase homolog LSD1The histone demethylase LSD1/KDM1A promotes the DNA damage responseLysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.
P921
Q50252765-777624A0-D8FE-45B9-A831-B21EA3A5A011Q50252766-13300582-34E2-4EBC-B6B5-251F19945D79Q50252774-72C51801-BA17-452B-B861-3129E2B933D1Q50274179-6824BE35-1ECC-4A80-85A5-7BA7D60EAF6DQ50274180-F9EA744D-2C20-464A-81B1-CF503BE306CAQ50299179-6337D466-24D6-444D-99E7-F6CF8C1992C8Q50299181-D93512A2-C85C-4F5C-B8A9-2113EAACAB84Q55192617-7466D868-C12F-4520-AE24-413D3C0D6254Q55219943-9A32346D-A017-49BE-9082-A1BEB1E75879Q55219944-FB0E7089-35D3-48C4-A9D7-E07C85DF6F78
P527
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Lysine demethylase 1A
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Lysine demethylase 1A
@en
type
label
Lysine demethylase 1A
@en
altLabel
BRAF35-HDAC complex protein BHC110
@en
FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
@en
KDM1A
@en
amine oxidase (flavin containing) domain 2
@en
flavin-containing amine oxidase domain-containing protein 2
@en
lysine (K)-specific demethylase 1A
@en
lysine-specific histone demethylase 1
@en
lysine-specific histone demethylase 1A
@en
prefLabel
Lysine demethylase 1A
@en
P361
P637
P638
P680
P681
P682
P705
P352
P31
P352
P361
P637
NP_001009999
NP_001350583
XP_005245843
XP_006710536
XP_006710537
XP_016856205
XP_016856206
P638
P680
P681
P682
P702
P703
P705
ENSP00000349049
ENSP00000383042
ENSP00000473294
ENSP00000473297