Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia - Wikidata - thesis-toulmin - TriplyDB

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

http://www.wikidata.org/entity/Q21128676

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Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation Alcoholic Liver Disease: Update on the Role of Dietary Fat The perception and endogenous modulation of pain Prolactin receptor in regulation of neuronal excitability and channels Atypical sensors for direct and rapid neuronal detection of bacterial pathogens Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model TRP channels and traffic-related environmental pollution-induced pulmonary disease Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease Review of overlap between thermoregulation and pain modulation in fibromyalgia.Transient receptor potential (TRP) channels: a clinical perspective Peripheral gating of pain signals by endogenous lipid mediators.The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity.Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.Nitro-oleic acid inhibits firing and activates TRPV1- and TRPA1-mediated inward currents in dorsal root ganglion neurons from adult male rats.Additive antinociceptive effects of a combination of vitamin C and vitamin E after peripheral nerve injury.TRPA1 is a polyunsaturated fatty acid sensor in mammals Are sensory TRP channels biological alarms for lipid peroxidation?Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease Orofacial pain Fish oil concentrate delays sensitivity to thermal nociception in mice.Low omega-6 vs. low omega-6 plus high omega-3 dietary intervention for chronic daily headache: protocol for a randomized clinical trial.The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury.Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease.Serotonin increases the functional activity of capsaicin-sensitive rat trigeminal nociceptors via peripheral serotonin receptors.Serum levels of oxylipins in achilles tendinopathy: an exploratory study.Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.A simple and inexpensive method for determining cold sensitivity and adaptation in mice.Fragile X mental retardation protein (FMRP) and the spinal sensory system.Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1.Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms.

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P2860

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

http://www.wikidata.org/entity/Q21128676

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2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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Activation of TRPV1 in the spi ...... s to inflammatory hyperalgesia

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Activation of TRPV1 in the spi ...... s to inflammatory hyperalgesia

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Activation of TRPV1 in the spi ...... s to inflammatory hyperalgesia

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Activation of TRPV1 in the spi ...... s to inflammatory hyperalgesia

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Proceedings of the National Academy of Sciences of the United States of America

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Activation of TRPV1 in the spi ...... s to inflammatory hyperalgesia

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Amol M Patwardhan

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Armen N Akopian

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Kenneth M Hargreaves

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Phoebe E Scotland

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P2860

The capsaicin receptor: a heat-activated ion channel in the pain pathway

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors.

Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors

Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme

TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists

TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications

Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A

Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances

Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesia

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