Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart
about
Altered DNA methylation in leukocytes with trisomy 21Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic diseaseFunctional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetusesEvolution of the neocortex: a perspective from developmental biologyIntegrated analysis of DNA copy number and gene expression microarray data using gene setsValidation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome.Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomyProfiling expression changes caused by a segmental aneuploid in maize.Identification of dysregulated genes in lymphocytes from children with Down syndrome.Effects of aneuploidy on genome structure, expression, and interphase organization in Arabidopsis thaliana.Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.A critical period in cortical interneuron neurogenesis in down syndrome revealed by human neural progenitor cells.Using systems biology to simplify complex disease: immune cartography.Integrated analysis of gene expression and copy number data on gene shaving using independent component analysisGene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening.Ohnologs in the human genome are dosage balanced and frequently associated with disease.Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome.Molecular signatures of cardiac defects in Down syndrome lymphoblastoid cell lines suggest altered ciliome and Hedgehog pathways.Genome-wide expression analysis in Down syndrome: insight into immunodeficiency.Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies.Expression signature as a biomarker for prenatal diagnosis of trisomy 21.Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes.Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21Gene expression variation in Down's syndrome mice allows prioritization of candidate genesNatural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalanceClassification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypesThe power of comparative and developmental studies for mouse models of Down syndromeMolecular and cellular alterations in Down syndrome: toward the identification of targets for therapeuticsTranscriptional consequences of aneuploidy.Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination.Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome.Validation of computational methods in genomics.Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombinationConstitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidyAn Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome.Trisomy 21 and Down syndrome: a short review.
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P2860
Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Primary and secondary transcri ...... Down syndrome brain and heart
@ast
Primary and secondary transcri ...... Down syndrome brain and heart
@en
Primary and secondary transcri ...... Down syndrome brain and heart
@en-gb
Primary and secondary transcri ...... Down syndrome brain and heart
@nl
type
label
Primary and secondary transcri ...... Down syndrome brain and heart
@ast
Primary and secondary transcri ...... Down syndrome brain and heart
@en
Primary and secondary transcri ...... Down syndrome brain and heart
@en-gb
Primary and secondary transcri ...... Down syndrome brain and heart
@nl
prefLabel
Primary and secondary transcri ...... Down syndrome brain and heart
@ast
Primary and secondary transcri ...... Down syndrome brain and heart
@en
Primary and secondary transcri ...... Down syndrome brain and heart
@en-gb
Primary and secondary transcri ...... Down syndrome brain and heart
@nl
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P2860
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P1476
Primary and secondary transcri ...... Down syndrome brain and heart
@en
P2093
Edward L Spitznagel
Huashi Ding
Ingo Ruczinski
Jason C Ting
Jonathan Pevsner
Jung-whan Kim
Laurence P Frelin
Thomas J Downey
Xiaowen Wang
P2860
P2888
P3181
P356
10.1186/GB-2005-6-13-R107
P407
P577
2005-12-16T00:00:00Z