Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells - Wikidata - thesis-toulmin - TriplyDB

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

http://www.wikidata.org/entity/Q21195236

about

Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase Invasion of breast cancer cells into collagen matrix requires TGF-α and Cdc42 signaling RAC3 is a pro-migratory co-activator of ERα A computer-assisted 3D model for analyzing the aggregation of tumorigenic cells reveals specialized behaviors and unique cell types that facilitate aggregate coalescence ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer.A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation.The tumor suppressor role of miR-124 in osteosarcoma Gbetagamma signaling promotes breast cancer cell migration and invasion.Phosphorylation of Cdc42 effector protein-4 (CEP4) by protein kinase C promotes motility of human breast cells The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines Expression of Rac-1 related to tumor depth, lymph node metastasis and patient prognosis in esophageal squamous cell carcinoma.Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry.Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer.Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway.Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines.Rac signaling in breast cancer: a tale of GEFs and GAPs.Association of RAC1 Gene Polymorphisms with Primary End-Stage Renal Disease in Chinese Renal Recipients.Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity.Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44.p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer.Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.Cooperate concept of metastasis: site-specific requirement of activated differentiation and dynamic deterioration.Occurrence and significance of epithelial-mesenchymal transition in breast cancer.RAC1: an emerging therapeutic option for targeting cancer angiogenesis and metastasis.Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression.Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.Rac1 modulates the vitreous-induced plasticity of mesenchymal movement in retinal pigment epithelial cells.The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells.Rac1 is a potential target to circumvent radioresistance

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P2860

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

http://www.wikidata.org/entity/Q21195236

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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name

Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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type

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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Breast Cancer Research

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Rac1 and Rac3 isoform activati ...... e of human breast cancer cells

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P2093

Janet E Price

http://www.w3.org/2001/XMLSchema#string

Paige J Baugher

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Surangani F Dharmawardhane

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P2860

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.

Characterization of RAC3, a novel member of the Rho family

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

Inflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancers

Cell migration: integrating signals from front to back

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

Rho and Rac take center stage

Rho GTPases and cell migration

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

Rho GTPases: signaling, migration, and invasion.

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10.1186/BCR1329

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6

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Lakshmi Krishnamoorthy

Lakshmi Krishnamoorthy

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2005-09-30T00:00:00Z

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7488288

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1006808592

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16280046

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1410764

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