Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs
about
Minimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesThe study of psychiatric disease genes and drugs in zebrafishOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringA CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish.Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesisDysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair.Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9Patterns of CRISPR/Cas9 activity in plants, animals and microbesMicroarray Noninvasive Neuronal Seizure Recordings from Intact Larval ZebrafishCHOPCHOP v2: a web tool for the next generation of CRISPR genome engineeringHigh-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae.Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons.An enhanced vector-free allele exchange (VFAE) mutagenesis protocol for genome editing in a wide range of bacterial speciesnr3c1 null mutant zebrafish are viable and reveal DNA-binding-independent activities of the glucocorticoid receptor.A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome.Spell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders.Zebrafish Genome Engineering Using the CRISPR-Cas9 System.A novel model for development, organization, and function of gonadotropes in fish pituitary.Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.A mouse geneticist's practical guide to CRISPR applications.Engineered CRISPR-Cas9 nucleases with altered PAM specificitiesUnraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach.CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus.Whole-organism lineage tracing by combinatorial and cumulative genome editingDramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design.Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegyptiCRISPR/Cas9-mediated conversion of eGFP- into Gal4-transgenic lines in zebrafish.High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis.Antisense Oligonucleotide-Mediated Transcript Knockdown in ZebrafishReverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAsCRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates.mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish.Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish.CRISPR library designer (CLD): software for multispecies design of single guide RNA librariesEfficient generation of transgenic reporter strains and analysis of expression patterns in Caenorhabditis elegans using library MosSCIEvaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivoHomology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.
P2860
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P2860
Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs
description
2014 nî lūn-bûn
@nan
2014 թուականին հրատարակուած գիտական յօդուած
@hyw
2014 թվականին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@ast
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en-gb
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@nl
type
label
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@ast
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en-gb
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@nl
altLabel
Efficient Mutagenesis by Cas9 ...... ssessment of Single-Guide RNAs
@en
prefLabel
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@ast
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en-gb
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@nl
P2093
P2860
P50
P3181
P1433
P1476
Efficient mutagenesis by Cas9 ...... ssessment of single-guide RNAs
@en
P2093
Alexander F Schier
Andrea Pauli
Constance Richter
Laila Ahkmetova
Laila Akhmetova
Steven Zimmerman
Summer B Thyme
Tessa G Montague
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0098186
P407
P577
2014-01-01T00:00:00Z