Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
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The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideApolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's diseaseTREM2 Variants in Alzheimer's DiseaseVariant of TREM2 Associated with the Risk of Alzheimer's DiseaseThe genetic epidemiology of neurodegenerative disease.Subjective Memory Complaints and Cognitive Impairment in Older PeopleEpidemiology of neurodegeneration in American-style professional football playersAPOE -ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a community settingAPOE -ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a secondary care settingAPOE -ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a primary care settingGenetics of cognition in epilepsySORL1 variants and risk of late-onset Alzheimer's diseaseQuantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregationCLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXVIsoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer diseaseReduction in DHA transport to the brain of mice expressing human APOE4 compared to APOE2RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptorsMolecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer diseaseCLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrilsGGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β productionA polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease riskEvidence that the gene encoding insulin degrading enzyme influences human lifespanHuman APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer modelNeurogenetics. Triumphs and challengesIdentification of a non-canonical E-box motif as a regulatory element in the proximal promoter region of the apolipoprotein E geneThe apolipoprotein E gene, attention, and brain functionMetabolic dysfunction in Alzheimer's disease and related neurodegenerative disordersApolipoprotein E and Alzheimer diseaseApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyAmyloid beta-protein stimulates trafficking of cholesterol and caveolin-1 from the plasma membrane to the Golgi complex in mouse primary astrocytesThe Promises and Pitfalls of GenoeconomicsVariations in DNA elucidate molecular networks that cause diseaseAnalysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia riskAR, apoE, and cognitive functionProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseReelin signaling antagonizes beta-amyloid at the synapseGenome-wide association studies in Alzheimer's diseaseEndophenotypes in normal brain morphology and Alzheimer's disease: a reviewOccupational exposures to solvents and aluminium and estimated risk of Alzheimer's disease
P2860
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P2860
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@ast
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@en
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@nl
type
label
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@ast
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@en
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@nl
prefLabel
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@ast
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@en
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@nl
P2093
P2860
P3181
P356
P1476
Apolipoprotein E: high-avidity ...... set familial Alzheimer disease
@en
P2093
A M Saunders
D Schmechel
G S Salvesen
M Pericak-Vance
W J Strittmatter
P2860
P304
P3181
P356
10.1073/PNAS.90.5.1977
P407
P577
1993-03-01T00:00:00Z