Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain
about
Glycosaminoglycans and glycomimetics in the central nervous systemProteoglycans in the central nervous system: role in development, neural repair, and Alzheimer's diseaseDisruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 alleleMelanopsin retinal ganglion cell loss and circadian dysfunction in Alzheimer's disease (Review)Amyloid as a depot for the formulation of long-acting drugsAgrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clustersInduction of filopodia-like protrusions by transmembrane agrin: role of agrin glycosaminoglycan chains and Rho-family GTPasesAgrin in the Developing CNS: New Roles for a Synapse OrganizerVascular biomechanical properties in mice with smooth muscle specific deletion of Ndst1Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide.Defining elastic fiber interactions by molecular fishing: an affinity purification and mass spectrometry approach.Abnormal post-translational and extracellular processing of brevican in plaque-bearing mice over-expressing APPsw.Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma.Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis.Physiopathological modulators of amyloid aggregation and novel pharmacological approaches in Alzheimer's disease.Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.Inhibition of amyloid A amyloidogenesis in vivo and in tissue culture by 4-deoxy analogues of peracetylated 2-acetamido-2-deoxy-alpha- and beta-d-glucose: implications for the treatment of various amyloidoses.Changes in brain β-amyloid deposition and aquaporin 4 levels in response to altered agrin expression in miceCharacterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation.Polyanions and the proteome.Amyloid accomplices and enforcersRole of water-soluble amyloid-beta in the pathogenesis of Alzheimer's disease.Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cellsIncreased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat dietHeat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease.Heparin accelerates gelsolin amyloidogenesis.Abeta aggregation and possible implications in Alzheimer's disease pathogenesisCasting a net on dendritic spines: the extracellular matrix and its receptors.Misfolding of amyloidogenic proteins and their interactions with membranes.The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy.Protective Properties of Neural Extracellular Matrix.Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins.Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain.Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathwayOverexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.An investigation into the mechanisms mediating plasma lipoprotein-potentiated beta-amyloid fibrillogenesis.Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.Kinetics of glycosaminoglycan deposition in splenic AA amyloidosis induced in mink.
P2860
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P2860
Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@ast
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en-gb
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@nl
type
label
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@ast
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en-gb
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@nl
prefLabel
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@ast
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en-gb
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@nl
P2093
P356
P1476
Agrin binds to beta-amyloid (A ...... s in Alzheimer's disease brain
@en
P2093
P304
P356
10.1006/MCNE.1999.0816
P407
P577
2000-02-01T00:00:00Z