Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway
about
CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2)Thrombin regulates chemokine induction during human retinal pigment epithelial cell/monocyte interactionGenomewide trapping of genes that encode secreted and transmembrane proteins repressed by oncogenic signaling.Role of coagulation in the recruitment of colon adenocarcinoma cells to thrombus under shear.Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS.Transcriptional regulation via TF-modifying enzymes: an integrative model-based analysis.Major differences in the responses of primary human leukocyte subsets to IFN-beta.Suppression of activation of signal transducer and activator of transcription-5B signaling in the vessel wall reduces balloon injury-induced neointima formation.Genomic dissection of the cytokine-controlled STAT5 signaling network in liverWedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.Thrombin stimulation of inflammatory breast cancer cells leads to aggressiveness via the EGFR-PAR1-Pak1 pathwayThe 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8.Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models.Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cellsProcaspase 8 and Bax are up-regulated by distinct pathways in Streptococcal pyrogenic exotoxin B-induced apoptosis.Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia.Dabigatran antagonizes growth, cell-cycle progression, migration, and endothelial tube formation induced by thrombin in breast and glioblastoma cell lines.Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis.A lymph node metastatic mouse model reveals alterations of metastasis-related gene expression in metastatic human oral carcinoma sublines selected from a poorly metastatic parental cell line.p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway.Using global gene expression patterns to characterize Annexin V positive and negative human monocytes in culture.Red wine polyphenol extract efficiently protects intestinal epithelial cells from inflammation opposite modulation of JAK/STAT and Nrf2 pathwaysPAR4 overexpression promotes colorectal cancer cell proliferation and migrationCell proliferation in human ganglionic eminence and suppression after prematurity-associated haemorrhage
P2860
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P2860
Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@ast
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en-gb
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@nl
type
label
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@ast
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en-gb
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@nl
prefLabel
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@ast
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en-gb
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@nl
P2093
P2860
P921
P3181
P356
P1476
Thrombin inhibits tumor cell g ...... dent, STAT-1-dependent pathway
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.275.9.6462
P407
P577
2000-03-03T00:00:00Z