about
P688
Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodelingNF-kappaB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2AFunctional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2AMolecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscleMutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2ANovel variants of muscle calpain 3 identified in human melanoma cells: cisplatin-induced changes in vitro and differential expression in melanocytic lesionsMultiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscleImmunohistochemical analysis of calpain 3: advantages and limitations in diagnosing LGMD2ADef defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradationThe protease core of the muscle-specific calpain, p94, undergoes Ca2+-dependent intramolecular autolysis.
P921
Q24294688-874C9B47-B724-4936-A024-E6F173484363Q24303059-33C3E605-DB01-40D8-80ED-54D8A52D1FDDQ24310208-034D702D-D7BF-4D89-9EEE-B1B92C8F2F07Q24311822-EAB10A53-5740-4010-A373-483BCCB86708Q24314667-BB828DD6-F880-48AF-AF36-6186868901E9Q24318456-2844514A-C5C0-4686-B197-8A35938E4FC8Q24319118-5A81BCB6-A151-470C-82E3-26CB72D01B71Q24339386-6069F6F6-B311-43BB-A3AB-88E5C5E2DA60Q33112706-BC77B912-8E87-4D65-8FB4-7B17D113C973Q34164811-9BA68A2F-4BAE-4B86-A7D5-EAD2FF543C8D
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteïne in Calpain 3
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Calpain 3
@en
type
label
Calpain 3
@en
altLabel
CANP 3
@en
CAPN3
@en
Calcium-activated neutral proteinase 3
@en
Calpain L3
@en
Calpain p94
@en
Muscle-specific calcium-activated neutral protease 3
@en
calpain p94, large [catalytic] subunit
@en
calpain, large polypeptide L3
@en
calpain-3
@en
muscle-specific calcium-activated neutral protease 3 large subunit
@en
prefLabel
Calpain 3
@en
P361
P527
P637
P680
P681
P682
P705
P352
P638
P279
P31
P352
P361
P527
P637
P680
P681
P682
P702
P703
P705
ENSP00000183936
ENSP00000326281
ENSP00000336840
ENSP00000348667
ENSP00000350181
ENSP00000380349
ENSP00000380384
ENSP00000380387
ENSP00000454379
ENSP00000454937