Interindividual variance of cytochrome P450 forms in human hepatic microsomes: correlation of individual forms with xenobiotic metabolism and implications in risk assessment
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Application of an updated physiologically-based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and miceThe metabolic rate constants and specific activity of human and rat hepatic cytochrome P-450 2E1 toward toluene and chloroformActivity of Zearalenone in the Porcine Intestinal TractRadical induction theory of ulcerative colitisApplication of in vitro biotransformation data and pharmacokinetic modeling to risk assessment.Physicochemical and biological data for the development of predictive organophosphorus pesticide QSARs and PBPK/PD models for human risk assessment.Incorporation of pharmacokinetic and pharmacodynamic data into risk assessments.Bariatric surgery-induced weight loss reduces hepatic lipid peroxidation levels and affects hepatic cytochrome P-450 protein content.Issues in the pharmacokinetics of trichloroethylene and its metabolites.Optimization and validation of a label-free MRM method for the quantification of cytochrome P450 isoforms in biological samples.Relationship between genetic polymorphism of cytochrome P450IIE1 and fatty liver.Cytochrome P450 reaction-phenotyping: an industrial perspective.In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs.Curcumin, Piperine, and Capsaicin: A Comparative Study of Spice-Mediated Inhibition of Human Cytochrome P450 Isozyme Activities.Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse.Quantitative analysis of cytochrome P450 isoforms in human liver microsomes by the combination of proteomics and chemical probe-based assay.The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery.Age-related Differences in CYP3A Abundance and Activity in the Liver of the Göttingen Minipig.The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM).Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.In vitro metabolism of the fungicide and environmental contaminant trans-bromuconazole and implications for risk assessment.
P2860
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P2860
Interindividual variance of cytochrome P450 forms in human hepatic microsomes: correlation of individual forms with xenobiotic metabolism and implications in risk assessment
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Interindividual Variance of Cy ...... mplications in Risk Assessment
@nl
Interindividual variance of cy ...... mplications in risk assessment
@ast
Interindividual variance of cy ...... mplications in risk assessment
@en
Interindividual variance of cy ...... mplications in risk assessment
@en-gb
type
label
Interindividual Variance of Cy ...... mplications in Risk Assessment
@nl
Interindividual variance of cy ...... mplications in risk assessment
@ast
Interindividual variance of cy ...... mplications in risk assessment
@en
Interindividual variance of cy ...... mplications in risk assessment
@en-gb
prefLabel
Interindividual Variance of Cy ...... mplications in Risk Assessment
@nl
Interindividual variance of cy ...... mplications in risk assessment
@ast
Interindividual variance of cy ...... mplications in risk assessment
@en
Interindividual variance of cy ...... mplications in risk assessment
@en-gb
P921
P356
P1476
Interindividual variance of cy ...... mplications in risk assessment
@en
P2093
John C. Lipscomb
P2880
P304
P356
10.1006/RTPH.2000.1424
P407
P577
2000-10-01T00:00:00Z