Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples

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http://www.wikidata.org/entity/Q24289511

Q24289511

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Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development Parkinson's Disease: The Mitochondria-Iron Link Individuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology Regulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseases The role of iron-induced fibrin in the pathogenesis of Alzheimer's disease and the protective role of magnesium Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury Targeting the redox balance in inflammatory skin conditions Multiple sclerosis: molecular mechanisms and therapeutic opportunities Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery Ferritin couples iron and fatty acid metabolism A Dormant Microbial Component in the Development of Preeclampsia Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing Formation of hydroxyl radical from San Joaquin Valley particles extracted in a cell-free surrogate lung fluid A Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease The role of iron in neurodegenerative disorders: insights and opportunities with synchrotron light.Expression and localization of mitochondrial ferritin mRNA in Alzheimer's disease cerebral cortex.Prion protein regulates iron transport by functioning as a ferrireductase.Targeting iron metabolism in drug discovery and delivery Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders.Iron metabolism disturbance in a French cohort of ALS patients Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress The role of iron in the immune response to bacterial infection The oxidative damage initiation hypothesis for meiosis.Iron and mechanisms of neurotoxicity The dormant blood microbiome in chronic, inflammatory diseases.Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Iron status in HIV-1 infection: implications in disease pathology.MR susceptibility imaging.Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.Eryptosis as a marker of Parkinson's disease Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.An analysis of a 'community-driven' reconstruction of the human metabolic network Carnosine's effect on amyloid fibril formation and induced cytotoxicity of lysozyme.Dysregulated iron metabolism in the choroid plexus in fragile X-associated tremor/ataxia syndrome Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics Astrocytic P2Y(1) receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia.Iron and neurodegeneration in multiple sclerosis.Effects of a Novel Dental Gel on Plaque and Gingivitis: A Comparative Study Dopaminergic Neurons Respond to Iron-Induced Oxidative Stress by Modulating Lipid Acylation and Deacylation Cycles.On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.

P2860

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P2860

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples

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http://www.wikidata.org/entity/Q24289511

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2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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