LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome
about
Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore functionThe essential role of centrosomal NDE1 in human cerebral cortex neurogenesisSilencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Mitotic control of kinetochore-associated dynein and spindle orientation by human SpindlyNdel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity.Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylationNudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assemblyHuman Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindleTreacher Collins syndrome: etiology, pathogenesis and preventionNudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dyneinSevere NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stagesMolecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical DevelopmentStructural features and chaperone activity of the NudC protein family.Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.NudEL targets dynein to microtubule ends through LIS1.14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndromeMutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humansThe DISC locus in psychiatric illnessRegulators of the cytoplasmic dynein motorDISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illnessDISC1-binding proteins in neural development, signalling and schizophreniaLis1 is necessary for normal non-radial migration of inhibitory interneuronsCytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway.SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in miceTargeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerizationLis1-Nde1-dependent neuronal fate control determines cerebral cortical size and laminationNDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitmentTargeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesisInactivation of a testis-specific Lis1 transcript in mice prevents spermatid differentiation and causes male infertilityComplete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transportHeterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive MemoryThe N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein.CLIP-170 homologue and NUDE play overlapping roles in NUDF localization in Aspergillus nidulansRoles of NUDE and NUDF proteins of Aspergillus nidulans: insights from intracellular localization and overexpression effectsMyosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration.Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation.Leading process branch instability in Lis1+/- nonradially migrating interneuronsLIS1 and NudE induce a persistent dynein force-producing stateNdel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon.
P2860
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P248
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P2860
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
LIS1 regulates CNS lamination ...... al component of the centrosome
@ast
LIS1 regulates CNS lamination ...... al component of the centrosome
@en
LIS1 regulates CNS lamination ...... al component of the centrosome
@en-gb
LIS1 regulates CNS lamination ...... al component of the centrosome
@nl
type
label
LIS1 regulates CNS lamination ...... al component of the centrosome
@ast
LIS1 regulates CNS lamination ...... al component of the centrosome
@en
LIS1 regulates CNS lamination ...... al component of the centrosome
@en-gb
LIS1 regulates CNS lamination ...... al component of the centrosome
@nl
prefLabel
LIS1 regulates CNS lamination ...... al component of the centrosome
@ast
LIS1 regulates CNS lamination ...... al component of the centrosome
@en
LIS1 regulates CNS lamination ...... al component of the centrosome
@en-gb
LIS1 regulates CNS lamination ...... al component of the centrosome
@nl
P2093
P921
P3181
P1433
P1476
LIS1 regulates CNS lamination ...... al component of the centrosome
@en
P2093
L A Flanagan
M W Kirschner
P T Stukenberg
P304
P3181
P356
10.1016/S0896-6273(00)00145-8
P407
P577
2000-12-01T00:00:00Z