Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
about
XIAP: cell death regulation meets copper homeostasisA novel role for XIAP in copper homeostasis through regulation of MURR1Caspases: pharmacological manipulation of cell deathInhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.Upstream regulatory role for XIAP in receptor-mediated apoptosisHuman inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyThe anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sitesUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisPhotoreceptor cell death and rescue in retinal detachment and degenerationsStructural basis for the activation of human procaspase-7XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 DimerizationCrystal Structure of the BIR1 Domain of XIAP in Two Crystal FormsInteraction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein † ‡Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) †Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)The structure of XIAP BIR2: understanding the selectivity of the BIR domainsX-linked lymphoproliferative syndromes: brothers or distant cousins?Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesSTL-based analysis of TRAIL-induced apoptosis challenges the notion of type I/type II cell line classificationGene promoter of apoptosis inhibitory protein IAP2: identification of enhancer elements and activation by severe hypoxiaReaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibitionAn unconventional IAP-binding motif revealed by target-assisted iterative screening (TAIS) of the BIR3-cIAP1 domain.The 423Q polymorphism of the X-linked inhibitor of apoptosis gene influences monocyte function and is associated with periodic fever.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Quantitative analysis of pathways controlling extrinsic apoptosis in single cellsOvercoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells.A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy.Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiencyCyclopeptide Smac mimetics as antagonists of IAP proteins.XIAP impairs Smac release from the mitochondria during apoptosis.Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area.Lack of TNF-alpha promotes caspase-3-independent apoptosis during murine cytomegalovirus retinitis.Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression.XIAP reduces muscle proteolysis induced by CKD.Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.Structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1LSurvivin and IAP proteins in cell-death mechanismsFas death receptor signalling: roles of Bid and XIAP.
P2860
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P2860
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
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Structural basis of caspase in ...... e linker versus the BIR domain
@en-gb
Structural basis of caspase in ...... e linker versus the BIR domain
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prefLabel
Structural basis of caspase in ...... e linker versus the BIR domain
@ast
Structural basis of caspase in ...... e linker versus the BIR domain
@en
Structural basis of caspase in ...... e linker versus the BIR domain
@en-gb
Structural basis of caspase in ...... e linker versus the BIR domain
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P2093
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P1433
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Structural basis of caspase in ...... e linker versus the BIR domain
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P2093
P304
P3181
P356
10.1016/S0092-8674(02)02075-5
P407
P577
2001-03-09T00:00:00Z