Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase
about
Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function.A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgraftsInsulin-like growth factor system in cancer: novel targeted therapiesMutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincinComplex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachmentExpression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activityPregnancy associated plasma protein A2 (PAPP-A2) affects bone size and shape and contributes to natural variation in postnatal growth in miceDuplication and diversification of the hypoxia-inducible IGFBP-1 gene in zebrafishIdentification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterpartsMolecular analysis of ulilysin, the structural prototype of a new family of metzincin metalloproteases.Discovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A.Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease.Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activityFirst-trimester levels of pregnancy-associated plasma protein A2 (PAPP-A2) in the maternal circulation are elevated in pregnancies that subsequently develop preeclampsia.Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J).Altered placental expression of PAPPA2 does not affect birth weight in mice.Pregnancy associated plasma protein-A2: a novel biomarker for Down syndrome.IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells.PAPPA2, an enzyme that cleaves an insulin-like growth-factor-binding protein, is a candidate gene for a quantitative trait locus affecting body size in miceRegulation of pregnancy-associated plasma protein A2 (PAPPA2) in a human placental trophoblast cell line (BeWo).Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.The Impact of Preeclampsia on Gene Expression at the Maternal-Fetal Interface.Extracellular proteases as targets for drug developmentProteolytic degradation of insulin-like growth factor binding proteins by ovarian follicles: a control mechanism for selection of dominant follicles.IGFBP-5 Promotes Fibrosis Independently of Its Translocation to the Nucleus and Its Interaction with Nucleolin and IGF.The role of PAPP-A in the IGF system: location, location, location.Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid.Key questions and answers about pregnancy-associated plasma protein-A.Pappa2 deletion in mice affects male but not female fertilityUsing RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta.Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis.Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice.First Trimester Maternal Serum Screening Using Biochemical Markers PAPP-A and Free β-hCG for Down Syndrome, Patau Syndrome and Edward SyndromePappa2 is linked to salt-sensitive hypertension in Dahl S rats.Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability.Differential expression of human placental PAPP-A2 over gestation and in preeclampsiaMultifunctional roles of insulin-like growth factor binding protein 5 in breast cancer.
P2860
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P2860
Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@ast
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en-gb
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@nl
type
label
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@ast
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en-gb
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@nl
prefLabel
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@ast
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en-gb
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@nl
P2093
P2860
P921
P356
P1476
Pregnancy-associated plasma pr ...... r-binding protein-5 proteinase
@en
P2093
C A Conover
L S Laursen
L Sottrup-Jensen
M T Overgaard
P2860
P304
P356
10.1074/JBC.M102191200
P407
P577
2001-06-15T00:00:00Z