Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
about
Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondriaGenealogy of an ancient protein family: the Sirtuins, a family of disordered membersLysine glutarylation is a protein posttranslational modification regulated by SIRT5SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathwaysSirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activitySIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysineEffects of Oxidative Stress on Mesenchymal Stem Cell BiologyEmerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersSirtuin functions and modulation: from chemistry to the clinicSirtuins Link Inflammation and MetabolismPotential Modulation of Sirtuins by Oxidative StressBiochemical Genetic Pathways that Modulate Aging in Multiple SpeciesIntricate Roles of Mammalian Sirtuins in Defense against Viral PathogensEvolution and functional cross-talk of protein post-translational modificationsStructural basis for sirtuin activity and inhibitionForever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegenerationSirtuins as regulators of metabolism and healthspanTargeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsTargeting sirtuin 1 to improve metabolism: all you need is NAD(+)?Sirtuins in hematological aging and malignancyMitochondrial biogenesis through activation of nuclear signaling proteinsInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingMetabolism, longevity and epigeneticsGenetic code expansion as a tool to study regulatory processes of transcriptionSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismSirtuins, metabolism, and DNA repairLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationFrom sirtuin biology to human diseases: an updateNonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylasesSirtuins in epigenetic regulationSirtuin-dependent epigenetic regulation in the maintenance of genome integrityProtein lysine acylation and cysteine succination by intermediates of energy metabolismStructure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesisSuccinylome analysis reveals the involvement of lysine succinylation in metabolism in pathogenic Mycobacterium tuberculosisThe Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)A Molecular Mechanism for Direct Sirtuin Activation by ResveratrolEx-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanismStructural and Functional Analysis of Human SIRT1Structural basis for the site-specific incorporation of lysine derivatives into proteinsStructures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism
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P2860
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@ast
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en-gb
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@nl
type
label
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@ast
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en-gb
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@nl
altLabel
Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
@en
prefLabel
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@ast
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en-gb
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
@en
P2093
Brian Hyun Choi
Hening Lin
Hong Jiang
Jintang Du
Jiu Jiu Yu
Jun Huyn Kim
Richard A Cerione
P2860
P3181
P356
10.1126/SCIENCE.1207861
P407
P577
2011-11-11T00:00:00Z