Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
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Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferationMICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosisThreonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylationNuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma bruceiMob as tumor suppressor is activated by Hippo kinase for growth inhibition in DrosophilaThe Roles of NDR Protein Kinases in Hippo SignallingMechanisms of Hippo pathway regulationMammalian Hippo signalling: a kinase network regulated by protein-protein interactionsMitotic exit and separation of mother and daughter cellsNCP1/AtMOB1A Plays Key Roles in Auxin-Mediated Arabidopsis DevelopmentChemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine developmentThe promotion of neurite formation in Neuro2A cells by mouse Mob2 proteinCharacterization and evolution of the cell cycle-associated mob domain-containing proteins in eukaryotesThe tricornered Ser/Thr protein kinase is regulated by phosphorylation and interacts with furry during Drosophila wing hair developmentA genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases.Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis.Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling.MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.LATS1 phosphorylates forkhead L2 and regulates its transcriptional activity.Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.NDR kinases regulate essential cell processes from yeast to humans.Hippo signaling: growth control and beyond.Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.NDR functions as a physiological YAP1 kinase in the intestinal epithelium.The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism.Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosisStructural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signalingThe Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations.Phosphoregulation of Cbk1 is critical for RAM network control of transcription and morphogenesisThe N-terminal region of the Neurospora NDR kinase COT1 regulates morphology via its interactions with MOB2A/B.Two NDR kinase-MOB complexes function as distinct modules during septum formation and tip extension in Neurospora crassa.Protein kinases of the Hippo pathway: regulation and substrates.Cyclin D1 promotes cell cycle progression through enhancing NDR1/2 kinase activity independent of cyclin-dependent kinase 4Disease implication of hyper-Hippo signalling.Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes.
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P2860
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
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2004 nî lūn-bûn
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2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2004 թվականի օգոստոսին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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name
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@ast
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en-gb
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@nl
type
label
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@ast
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en-gb
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@nl
prefLabel
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@ast
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en-gb
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@nl
P2093
P2860
P3181
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P1476
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
@en
P2093
Brian A Hemmings
Mario R Stegert
Rastislav Tamaskovic
Samuel J Bichsel
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P304
P3181
P356
10.1074/JBC.M404542200
P407
P577
2004-08-20T00:00:00Z