SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
about
Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcriptionDeacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradationAutoacetylation of the histone acetyltransferase Rtt109Chromatin regulation and genome maintenance by mammalian SIRT6Sirtuin 1 and sirtuin 3: physiological modulators of metabolismSirtuins in hematological aging and malignancyHistone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferasesSirtuins in epigenetic regulationSirtuin-dependent epigenetic regulation in the maintenance of genome integrityA human tRNA synthetase is a potent PARP1-activating effector target for resveratrolDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsIntrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau FragmentationConserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family MembersA potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease.Structure and function of histone acetyltransferase MOFRational design and validation of a Tip60 histone acetyltransferase inhibitor.Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.Histone H2A.Z deregulation in prostate cancer. Cause or effect?Bacterial protein acetylation: the dawning of a new age.A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication.Function of the active site lysine autoacetylation in Tip60 catalysis.The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damageModulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatinDifferential effects on p53-mediated cell cycle arrest vs. apoptosis by p90.Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival.New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor.Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cellsAutoacetylation of the MYST lysine acetyltransferase MOF proteinQuantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.Nuclear receptor coactivators: structural and functional biochemistry.Acetylation reduces SOX9 nuclear entry and ACAN gene transactivation in human chondrocytes.Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).SIRT2 directs the replication stress response through CDK9 deacetylation.Estrogen receptor β (ERβ1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent mannerSIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases.Acetyltransferases (HATs) as targets for neurological therapeuticsSIRT1/PARP1 crosstalk: connecting DNA damage and metabolism.Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.
P2860
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P2860
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@ast
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en-gb
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@nl
type
label
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@ast
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en-gb
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@nl
prefLabel
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@ast
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en-gb
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@nl
P2860
P921
P3181
P356
P1476
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60
@en
P2093
Jiadong Wang
Junjie Chen
P2860
P304
P3181
P356
10.1074/JBC.M109.087585
P407
P577
2010-04-09T00:00:00Z