Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
about
MARCH5 inactivation supports mitochondrial function during neurodegenerative stressMitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinMitophagy plays a central role in mitochondrial ageingCell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative diseaseMorphological control of mitochondrial bioenergeticsMitochondrial quality control: decommissioning power plants in neurodegenerative diseasesMechanisms of mitochondria and autophagy crosstalkPotentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression.Human mitochondrial Fis1 links to cell cycle regulators at G2/M transitionDynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseasesMitochondrial function in vascular endothelial cell in diabetesMitochondrial Metabolism in Aging HeartExploring new pathways of neurodegeneration in ALS: the role of mitochondria quality controlInhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXARegulation of Mitochondrial Dynamics by Dynamin-Related Protein-1 in Acute Cardiorenal SyndromeRegulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stabilityNear-atomic resolution structural model of the yeast 26S proteasome.MARCH5-mediated quality control on acetylated Mfn1 facilitates mitochondrial homeostasis and cell survival.Control of mitochondrial biogenesis and function by the ubiquitin-proteasome systemMitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins.Mitochondria in oocyte aging: current understandingRoles of mitochondrial ubiquitin ligase MITOL/MARCH5 in mitochondrial dynamics and diseases.TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expressionDownregulation of OPA3 is responsible for transforming growth factor-β-induced mitochondrial elongation and F-actin rearrangement in retinal pigment epithelial ARPE-19 cells.Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and functionMitochondrial effectors of cellular senescence: beyond the free radical theory of agingMitochondrial E3 ligase March5 maintains stemness of mouse ES cells via suppression of ERK signalling.Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin.Regulators of mitochondrial dynamics in cancer.Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia.Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 proteinStress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.Pleiotropic actions of estrogen: a mitochondrial matter.Modulation of Cell Cycle Profile by Chlorella vulgaris Prevents Replicative Senescence of Human Diploid Fibroblasts.β-Amyloid (Aβ) oligomers impair brain-derived neurotrophic factor retrograde trafficking by down-regulating ubiquitin C-terminal hydrolase, UCH-L1.From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling.Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function.
P2860
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P2860
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@ast
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en-gb
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@nl
type
label
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@ast
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en-gb
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@nl
prefLabel
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@ast
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en-gb
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@nl
P2093
P2860
P921
P3181
P356
P1476
Loss of MARCH5 mitochondrial E ...... ated protein 1 and mitofusin 1
@en
P2093
Hyeseong Cho
Mariusz Karbowski
Richard J Youle
Seungmin Lee
Yong-Yea Park
P2860
P304
P3181
P356
10.1242/JCS.061481
P407
P577
2010-01-26T00:00:00Z