The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link
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A sulfilimine bond identified in collagen IVDevelopmental and pathogenic mechanisms of basement membrane assemblyIdentification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activityCrystal Structure of Human Collagen XVIII Trimerization Domain: A Novel Collagen Trimerization FoldCrystal structure of the human collagen XV trimerization domain: A potent trimerizing unit common to multiplexin collagensThe crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus shows significant similarity to immunomodulatory HIV protein gp41Highly reinforced structure of a C-terminal dimerization domain in von Willebrand factorMammalian collagen IVNovel covalent bond in proteins: calculations on model systems question the bond stability.The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links.A novel COL4A1 frameshift mutation in familial kidney disease: the importance of the C-terminal NC1 domain of type IV collagenDefining elastic fiber interactions by molecular fishing: an affinity purification and mass spectrometry approach.Detection of differentially expressed basal cell proteins by mass spectrometryAlport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo.Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis.Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.Basement membranes: cell scaffoldings and signaling platforms.New functional roles for non-collagenous domains of basement membrane collagensGoodpasture's disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis.Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus musculus: an extension of the Col4a1 allelic series and the identificatiZebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome.Structural basis for the functions of endogenous angiogenesis inhibitors.Molecular recognition in the assembly of collagens: terminal noncollagenous domains are key recognition modules in the formation of triple helical protomers.A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes.Structure and function of basement membranes.Averaged kick maps: less noise, more signal... and probably less bias.The collagen family.COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets.Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration.Noncollagenous region of the streptococcal collagen-like protein is a trimerization domain that supports refolding of adjacent homologous and heterologous collagenous domains.Quaternary organization of the goodpasture autoantigen, the alpha 3(IV) collagen chain. Sequestration of two cryptic autoepitopes by intrapromoter interactions with the alpha4 and alpha5 NC1 domains.Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.Impact of heparan sulfate chains and sulfur-mediated bonds on the mechanical properties of bovine lens capsule.Structural insight for chain selection and stagger control in collagen.MAIN software for density averaging, model building, structure refinement and validation.Surface-bound collagen 4 is significantly more stable than collagen 1.Structural analysis of the N-terminal fragment of the antiangiogenic protein endostatin: a molecular dynamics study.Identification of S-hydroxylysyl-methionine as the covalent cross-link of the noncollagenous (NC1) hexamer of the alpha1alpha1alpha2 collagen IV network: a role for the post-translational modification of lysine 211 to hydroxylysine 211 in hexamer asThe NC1 dimer of human placental basement membrane collagen IV: does a covalent crosslink exist?Endogenous Matrix-Derived Inhibitors of Angiogenesis.
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P2860
The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link
description
2002 nî lūn-bûn
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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
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2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
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P2093
P2860
P356
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The 1.9-A crystal structure of ...... of covalent Met-Lys cross-link
@en
P2093
Albert Ries
Gleb P Bourenkov
Hans D Bartunik
Karlheinz Mann
Klaus Kühn
Manuel E Than
Robert Huber
Rupert Timpl
Stefan Henrich
P2860
P304
P356
10.1073/PNAS.062183499
P407
P50
P577
2002-05-01T00:00:00Z