Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease
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Classification of intrinsically disordered regions and proteinsDisruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsRegulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10Tankyrase 1 regulates centrosome function by controlling CPAP stabilityWnt/beta-catenin signaling and small molecule inhibitorsFunctions of PARylation in DNA Damage Repair PathwaysReaders of poly(ADP-ribose): designed to be fit for purposeRegulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin LigasesNon-transcriptional interactions of Hox proteins: inventory, facts, and future directionsTankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lockpara-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitorsHistory and progression of Fat cadherins in health and diseaseIdentification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-AcyltransferasesThe adaptor 3BP2 is required for KIT receptor expression and human mast cell survivalEtanercept administration to neonatal SH3BP2 knock-in cherubism mice prevents TNF-α-induced inflammation and bone loss.SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.The adaptor 3BP2 is required for early and late events in FcεRI signaling in human mast cells.Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage.Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model.Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function.Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cellsProteasome regulation by ADP-ribosylationSH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis modelInsights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy.Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.Large-scale preparation and characterization of poly(ADP-ribose) and defined length polymers.Battle between influenza A virus and a newly identified antiviral activity of the PARP-containing ZAPL protein.Targeting Wnt pathways in disease.Wnt pathway activation by ADP-ribosylation.Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutationsStructural Implications for Selective Targeting of PARPs.Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.Reprogramming cellular events by poly(ADP-ribose)-binding proteinsPARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis.Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.
P2860
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P248
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P2860
Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural basis and sequence ...... he basis for cherubism disease
@ast
Structural basis and sequence ...... he basis for cherubism disease
@en
Structural basis and sequence ...... he basis for cherubism disease
@en-gb
Structural basis and sequence ...... he basis for cherubism disease
@nl
type
label
Structural basis and sequence ...... he basis for cherubism disease
@ast
Structural basis and sequence ...... he basis for cherubism disease
@en
Structural basis and sequence ...... he basis for cherubism disease
@en-gb
Structural basis and sequence ...... he basis for cherubism disease
@nl
prefLabel
Structural basis and sequence ...... he basis for cherubism disease
@ast
Structural basis and sequence ...... he basis for cherubism disease
@en
Structural basis and sequence ...... he basis for cherubism disease
@en-gb
Structural basis and sequence ...... he basis for cherubism disease
@nl
P2093
P50
P3181
P1433
P1476
Structural basis and sequence ...... he basis for cherubism disease
@en
P2093
Andy Scotter
Gerald Gish
Jose LaRose
P304
P3181
P356
10.1016/J.CELL.2011.10.046
P407
P577
2011-12-09T00:00:00Z