Active site remodelling accompanies thioester bond formation in the SUMO E1
about
Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library designK11-linked ubiquitin chains as novel regulators of cell divisionAdvances in the development of SUMO specific protease (SENP) inhibitorsCrystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo PathwaysNoncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structuresAtg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy PathwayInsights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester TransferStructural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein DomainsRecognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein DomainsStructure of the ubiquitin-activating enzyme loaded with two ubiquitin moleculesExpression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymesRole of the Zn(2+) motif of E1 in SUMO adenylationThe SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (e1)Perilous journey: a tour of the ubiquitin-proteasome systemA Chemical and Enzymatic Approach to Study Site-Specific SumoylationProbes of ubiquitin E3 ligases enable systematic dissection of parkin activationSmall-molecule activation of SERCA2a SUMOylation for the treatment of heart failure.Structural and functional insights to ubiquitin-like protein conjugation.Protein neddylation: beyond cullin-RING ligases.Elevated global SUMOylation in Ubc9 transgenic mice protects their brains against focal cerebral ischemic damage.Twists and turns in ubiquitin-like protein conjugation cascades.Mechanism of E1-E2 interaction for the inhibition of Ubl adenylationNeuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases.Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions.Macromolecular juggling by ubiquitylation enzymes.SUMO-mimicking peptides inhibiting protein SUMOylation.Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosaAn in vitro Förster resonance energy transfer-based high-throughput screening assay for inhibitors of protein-protein interactions in SUMOylation pathway.Stable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesisUsing protein motion to read, write, and erase ubiquitin signals.Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage displayStreamlined expressed protein ligation using split inteins.
P2860
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P248
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P2860
Active site remodelling accompanies thioester bond formation in the SUMO E1
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Active site remodelling accompanies thioester bond formation in the SUMO E1
@ast
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en-gb
Active site remodelling accompanies thioester bond formation in the SUMO E1
@nl
type
label
Active site remodelling accompanies thioester bond formation in the SUMO E1
@ast
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en-gb
Active site remodelling accompanies thioester bond formation in the SUMO E1
@nl
prefLabel
Active site remodelling accompanies thioester bond formation in the SUMO E1
@ast
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en
Active site remodelling accompanies thioester bond formation in the SUMO E1
@en-gb
Active site remodelling accompanies thioester bond formation in the SUMO E1
@nl
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P2860
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P3181
P356
P1433
P1476
Active site remodelling accompanies thioester bond formation in the SUMO E1.
@en
P2093
Allan D Capili
Christopher D Lima
Derek S Tan
Shaun K Olsen
Xuequan Lu
P2860
P2888
P304
P3181
P356
10.1038/NATURE08765
P407
P577
2010-02-18T00:00:00Z
P5875
P6179
1001908526