Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain
about
Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco.Structure of IL-22 bound to its high-affinity IL-22R1 chainReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingStructure and Mechanism of Receptor Sharing by the IL-10R2 Common ChainCrystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potencyVirus-encoded homologs of cellular interleukin-10 and their control of host immune function.Domain-domain interactions underlying herpesvirus-human protein-protein interaction networks.Design and analysis of rhesus cytomegalovirus IL-10 mutants as a model for novel vaccines against human cytomegalovirusEffect of host genetics on the development of cytomegalovirus retinitis in patients with AIDS.Structural analysis of cytokines comprising the IL-10 familyTargeting of viral interleukin-10 with an antibody fragment specific to damaged arthritic cartilage improves its therapeutic potencySecretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia coli via a modified Sec-dependent transporter constructPurification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex.Cytokine homologs of human gammaherpesviruses.The molecular basis of IL-10 function: from receptor structure to the onset of signaling.Identification and characterization of a +1 frameshift observed during the expression of Epstein-Barr virus IL-10 in Escherichia coli.Epstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling propertiesBinding of interferon reduces the force of unfolding for interferon receptor 1.Viable Borrelia burgdorferi enhances interleukin-10 production and suppresses activation of murine macrophages.Dithiocarbamates and viral IL-10 collaborate in the immortalization and evasion of immune response in EBV-infected human B lymphocytes.Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.Inflamed gut mucosa: downstream of interleukin-10.Proteins: form and function.Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.The next generation of similarity measures that fully explore the semantics in biomedical ontologies.Identifying functionally important cis-peptide containing segments in proteins and their utility in molecular function annotation.A workflow for in silico design of hIL-10 and ebvIL-10 inhibitors using well-known miniprotein scaffolds.Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures.IL-10: A Multifunctional Cytokine in Viral Infections.Sequence variation of Epstein-Barr virus (EBV) BCRF1 in lymphomas in non-endemic areas of nasopharyngeal carcinoma.Peptide matching between Epstein-Barr virus and human proteins.Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1.Interleukin 2 Secretion by T Cells for Detection of Biologically Active Staphylococcal Enterotoxin Type E.Mapping Determinants of Cytokine Signaling via Protein Engineering
P2860
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P2860
Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Same structure, different func ...... d to the soluble IL-10R1 chain
@ast
Same structure, different func ...... d to the soluble IL-10R1 chain
@en
Same structure, different func ...... d to the soluble IL-10R1 chain
@en-gb
Same structure, different func ...... d to the soluble IL-10R1 chain
@nl
type
label
Same structure, different func ...... d to the soluble IL-10R1 chain
@ast
Same structure, different func ...... d to the soluble IL-10R1 chain
@en
Same structure, different func ...... d to the soluble IL-10R1 chain
@en-gb
Same structure, different func ...... d to the soluble IL-10R1 chain
@nl
prefLabel
Same structure, different func ...... d to the soluble IL-10R1 chain
@ast
Same structure, different func ...... d to the soluble IL-10R1 chain
@en
Same structure, different func ...... d to the soluble IL-10R1 chain
@en-gb
Same structure, different func ...... d to the soluble IL-10R1 chain
@nl
P2093
P1433
P1476
Same structure, different func ...... d to the soluble IL-10R1 chain
@en
P2093
Brandi C Jones
Mark R Walter
Naomi J Logsdon
Sung Il Yoon
P304
P356
10.1016/J.STR.2005.01.016
P407
P577
2005-04-01T00:00:00Z