Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling
about
Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein couplingUnderstanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system.The pineal gland: A model for adrenergic modulation of ubiquitin ligasesHeterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor.Melatonin and pancreatic islets: interrelationships between melatonin, insulin and glucagonMelatonin receptor genes in vertebrates.Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer.G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives.Systematic protein-protein interaction mapping for clinically relevant human GPCRsEncoding and decoding photoperiod in the mammalian pars tuberalis.History and biological significance of GPCR heteromerization in the neuroendocrine system.Quinone reductase 2 as a promising target of melatonin therapeutic actions.Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation.The Pseudo signal peptide of the corticotropin-releasing factor receptor type 2A prevents receptor oligomerizationMelatonin receptors: molecular pharmacology and signaling in the context of system bias.Description of the constitutive activity of cloned human melatonin receptors hMT(1) and hMT(2) and discovery of inverse agonists.Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor.GPCR heterodimers: asymmetries in ligand binding and signalling output offer new targets for drug discovery.Valproic Acid Influences MTNR1A Intracellular Trafficking and Signaling in a β-Arrestin 2-Dependent Manner.The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gα(i/o) protein-independent pathway.Evidence for RGS4 modulation of melatonin and thyrotrophin signalling pathways in the pars tuberalis.[G protein-coupled receptors in the spot light].Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50.The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development.Expanding the Concept of G Protein-Coupled Receptor (GPCR) Dimer Asymmetry towards GPCR-Interacting Proteins.
P2860
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P2860
Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@ast
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en-gb
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@nl
type
label
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@ast
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en-gb
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@nl
prefLabel
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@ast
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en-gb
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@nl
P2093
P2860
P50
P356
P1433
P1476
Molecular organization and dyn ...... mers for RGS and G(i) coupling
@en
P2093
Avais M Daulat
Bernhard Bettler
Jean-Luc Guillaume
Klara Ivankova-Susankova
Maud Kamal
Nathalie Clement
Philippe Delagrange
Ralf Jockers
Rostislav Turecek
P2860
P304
P356
10.1038/EMBOJ.2010.236
P407
P577
2010-09-21T00:00:00Z