Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
about
Expanding the substantial interactome of NEMO using protein microarraysRegulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophagesTumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activationThe interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaBOligomerization of optineurin and its oxidative stress- or E50K mutation-driven covalent cross-linking: possible relationship with glaucoma pathologyNuclear tumor necrosis factor receptor-associated factor 6 in lymphoid cells negatively regulates c-Myb-mediated transactivation through small ubiquitin-related modifier-1 modificationNEMO stabilizes c-Myc through direct interaction in the nucleusUSP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMOSUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processingInvolvement of linear polyubiquitylation of NEMO in NF-kappaB activationLUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMOAutoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathwayInduction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stressSUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.Diversity of degradation signals in the ubiquitin-proteasome systemDNA double-strand breaks activate a multi-functional genetic program in developing lymphocytesSUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cellsRAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylationWhen ubiquitin meets NF-κB: a trove for anti-cancer drug developmentThe PIDDosome, DNA-damage-induced apoptosis and beyondNew approaches to radiation protectionDNA Damage: From Chronic Inflammation to Age-Related DeteriorationTo be an ally or an adversary in bladder cancer: the NF-κB story has not unfoldedTRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 LigaseRoles for NF-kappaB in nerve cell survival, plasticity, and diseaseSignals from within: the DNA-damage-induced NF-kappaB responseGood cop, bad cop: the different faces of NF-kappaBComplex SUMO-1 regulation of cardiac transcription factor Nkx2-5A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defenceQuantification of cellular NEMO content and its impact on NF-κB activation by genotoxic stressSYT-SSX1 (synovial sarcoma translocated) regulates PIASy ligase activity to cause overexpression of NCOA3 proteinSUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cellsUbiquitin signalling in the NF-kappaB pathwayTranscription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.Binding Site Configurations Probe the Structure and Dynamics of the Zinc Finger of NEMO (NF-κB Essential Modulator).Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.A role for IkappaB kinase 2 in bipolar spindle assembly.Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell deathRegulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO.
P2860
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P2860
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Sequential modification of NEM ...... activation by genotoxic stress
@ast
Sequential modification of NEM ...... activation by genotoxic stress
@en
Sequential modification of NEM ...... activation by genotoxic stress
@en-gb
Sequential modification of NEM ...... activation by genotoxic stress
@nl
type
label
Sequential modification of NEM ...... activation by genotoxic stress
@ast
Sequential modification of NEM ...... activation by genotoxic stress
@en
Sequential modification of NEM ...... activation by genotoxic stress
@en-gb
Sequential modification of NEM ...... activation by genotoxic stress
@nl
prefLabel
Sequential modification of NEM ...... activation by genotoxic stress
@ast
Sequential modification of NEM ...... activation by genotoxic stress
@en
Sequential modification of NEM ...... activation by genotoxic stress
@en-gb
Sequential modification of NEM ...... activation by genotoxic stress
@nl
P2093
P3181
P1433
P1476
Sequential modification of NEM ...... activation by genotoxic stress
@en
P2093
Shelly M Wuerzberger-Davis
Shigeki Miyamoto
Tony T Huang
Zhao-Hui Wu
P304
P3181
P356
10.1016/S0092-8674(03)00895-X
P407
P577
2003-11-26T00:00:00Z