Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
about
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genesInteraction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase IICyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9)-cyclin T1 interaction in Nef-dependent mannerThe emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsThe LMO2 oncogene regulates DNA replication in hematopoietic cellsInduction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseCHD7 expression predicts survival outcomes in patients with resected pancreatic cancer.Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults.The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress.Involvement of cyclin K posttranscriptional regulation in the formation of Artemia diapause cystsA gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress responseA role for CDK9-cyclin K in maintaining genome integrityThr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase.Targeting cell cycle regulators in hematologic malignancies.ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.Complex effects of flavopiridol on the expression of primary response genesCyclin Dependent Kinase 9 Inhibitors for Cancer TherapyClassifying kinase conformations using a machine learning approach.A whole genome RNAi screen identifies replication stress response genes.ATR signalling: more than meeting at the fork.Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpointSIRT2 directs the replication stress response through CDK9 deacetylation.Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry.RNA polymerase II elongation control.Cyclin K goes with Cdk12 and Cdk13The enigmatic role of H2Bub1 in cancer.Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function.Human CDK18 promotes replication stress signaling and genome stability.BRCA1 recruitment to damaged DNA sites is dependent on CDK9.MicroRNA-874 inhibits cell proliferation and induces apoptosis in human breast cancer by targeting CDK9.Effects of Replication and Transcription on DNA Structure-Related Genetic InstabilityPhosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function.Inhibition of P-TEFb disrupts global transcription, oocyte maturation, and embryo development in the mouse.SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNASystematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.Distinct cyclin genes define each stage of ciliate conjugation.A role for CDK9 in UV damage response.A stitch in time and CDK9.
P2860
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P2860
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@ast
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en-gb
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@nl
type
label
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@ast
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en-gb
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@nl
prefLabel
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@ast
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en-gb
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
@en
P2093
David Cortez
David S Yu
Emory L Hsu
Jennifer Cayer
Runxiang Zhao
P2860
P304
P3181
P356
10.1038/EMBOR.2010.153
P407
P577
2010-11-01T00:00:00Z