In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
about
Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive valueTCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cellsPhysiologic characterization of type 2 diabetes-related lociGenetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageingZinc and diabetes mellitus: understanding molecular mechanisms and clinical implicationsZinc transporter 8 (ZnT8) and β cell functionNovel diabetes autoantibodies and prediction of type 1 diabetesThe physiological effects of deleting the mouse SLC30A8 gene encoding zinc transporter-8 are influenced by gender and genetic backgroundStructure of the zinc transporter YiiPStructural basis for autoregulation of the zinc transporter YiiPInsulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variantsZinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantationZinc transporters and zinc signaling: new insights into their role in type 2 diabetesAccumulation of cadmium in insulin-producing β cellsDeletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretionG protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunctionDown-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretionZinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?Genome-wide association studies in type 2 diabetesA genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variantsThree-dimensional structure of beta-cell-specific zinc transporter, ZnT-8, predicted from the type 2 diabetes-associated gene variant SLC30A8 R325W.Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearancePolymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.The influence of rare genetic variation in SLC30A8 on diabetes incidence and β-cell function.Zinc transporters and their role in the pancreatic β-cell.Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.The MafA transcription factor becomes essential to islet β-cells soon after birth.Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and NickelSome dietary factors can modulate the effect of the zinc transporters 8 polymorphism on the risk of metabolic syndromeLoss-of-function mutations in SLC30A8 protect against type 2 diabetesDetailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.Presence of diabetes autoantigens in extracellular vesicles derived from human islets.Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians.Zinc and human health: an update.The diagnostic value of zinc transporter 8 autoantibody (ZnT8A) for type 1 diabetes in Chinese.Protective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations.Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia).
P2860
Q21092217-B80B6FA5-9D70-4215-8305-467CADE70F4EQ24321979-1657ED02-325A-477E-A437-49CE6DC77434Q24630735-BD5B3212-C3F6-474B-9C27-70A36070EA2FQ26746405-513158D4-F4C5-4B7C-BC3E-DD1820298EB0Q26783573-45113FCF-1191-4E89-8AD4-B458BB951AACQ26829276-642BDB90-1A42-48BA-909E-073C85CA76E1Q27016130-E585301E-F1F9-4E03-BE29-A79EDCBB3A81Q27333587-B5230041-F82C-452D-A1ED-F5436984073CQ27647503-BFB1F2F4-6977-463C-AF7C-560C02492DD0Q27657426-450C0EB8-6D58-45BD-8F62-E1629B397F5BQ28249275-146EB962-6399-476F-B68B-0DCA056ED1B8Q28390590-3399F652-9D6E-4423-9D58-01950BDF998FQ28393509-EFD4B8B1-F517-4FAA-B61E-FBDB798D0E25Q28396021-E622782F-0903-4E85-ABFD-2E0C0B28A4C1Q28506358-441EAE5C-A6F4-400A-A654-3CF6991BFC55Q28511968-1DBDD37F-0A82-42B6-ADB3-78FC1BFB34C7Q28564600-F33AFE79-86A7-4631-9003-2F6BF1E35ED6Q28566179-D2C9D17F-449F-495B-8B2D-D68A70515E7CQ28752564-E77ACA40-1DE0-4B0A-AB94-C325A00BD8F7Q29547210-3F45C314-0AC7-4B64-817A-AA305E33710EQ30390030-01BC0844-8203-44BD-84EC-D07094BB474BQ30500111-59941577-5C65-4788-97A7-B3B344B11E62Q30547080-377AECF4-EF32-46F8-A7BA-2F9C236B0232Q33296991-F9D32D23-E30F-41E5-A9E7-0DEFE8304FE8Q33394569-2FEE291E-4059-4166-BDB1-DD466C6ABEACQ33459222-A260F4BB-E89F-46DE-87B0-2CD3DD663233Q33568942-20769223-D5AA-445C-9F51-65646A0F7B49Q33585706-776A1BAB-F3D6-4C60-87F9-B5B3E69CE355Q33593963-4BDACF72-79ED-4EA9-AE0B-9E11F346995CQ33646781-EF073676-895C-46E1-89F9-606083C6B0E4Q33671124-F77AFD8E-A481-483E-9B50-E3FA52BED5B6Q33687695-0D307EA2-F1A0-4D77-84C2-610C9802EA09Q33734046-ED24BD8B-7467-4C01-B18B-9CB2AADF7677Q33803511-419BCF79-6960-4624-879A-3B575A5F9D53Q33890308-BD5E30B5-DE1B-4CE8-8AD4-4894BF9E417DQ34024262-66605934-3850-4F76-99CB-ADEE81C06268Q34231267-8737DF7E-8025-4C77-A483-EBE185CF84F2Q34234608-2D17B331-7A27-4501-B697-F7740EB8CEA7Q34442232-95302178-3738-452E-BA59-AE8931BBF307Q34461210-46EF81E0-AE8D-40C4-A888-35B798B3BE15
P2860
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
In vivo expression and functio ...... cose-induced insulin secretion
@ast
In vivo expression and functio ...... cose-induced insulin secretion
@en
In vivo expression and functio ...... cose-induced insulin secretion
@nl
type
label
In vivo expression and functio ...... cose-induced insulin secretion
@ast
In vivo expression and functio ...... cose-induced insulin secretion
@en
In vivo expression and functio ...... cose-induced insulin secretion
@nl
prefLabel
In vivo expression and functio ...... cose-induced insulin secretion
@ast
In vivo expression and functio ...... cose-induced insulin secretion
@en
In vivo expression and functio ...... cose-induced insulin secretion
@nl
P2093
P50
P921
P3181
P356
P1476
In vivo expression and functio ...... cose-induced insulin secretion
@en
P2093
Alain Favier
Brigitte Vandewalle
Didier Grunwald
Julie Kerr-Conte
Rachel Garcia-Cuenca
Séverine Devergnas
P304
P3181
P356
10.1242/JCS.03164
P407
P577
2006-10-15T00:00:00Z