SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
about
Machine learning helps identify CHRONO as a circadian clock componentNetwork features of the mammalian circadian clockp75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networksRole of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 geneCircadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligaseSCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaFBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stressCompeting E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasmA positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machineryDual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clockCircadian clock control of the cellular response to DNA damageSetting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteinsDual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complexDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerCasein kinase 1 delta regulates the pace of the mammalian circadian clockA genome-wide RNAi screen for modifiers of the circadian clock in human cellsInterdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthCircadian Control of Global TranscriptionThe Molecular Circadian Clock and Alcohol-Induced Liver InjuryMolecular architecture of the mammalian circadian clockTime-of-day- and light-dependent expression of ubiquitin protein ligase E3 component N-recognin 4 (UBR4) in the suprachiasmatic nucleus circadian clockFunctional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromesSCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocketCrystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator ComplexCrystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligaseChemical chronobiology: Toward drugs manipulating time.Life in a dark biosphere: a review of circadian physiology in "arrhythmic" environments.Coupling circadian rhythms of metabolism and chromatin remodellingMolecular components of the circadian clock in mammalsTwo Distinct Types of E3 Ligases Work in Unison to Regulate Substrate UbiquitylationEmerging models for the molecular basis of mammalian circadian timingControl of chromosome stability by the beta-TrCP-REST-Mad2 axisReversible protein phosphorylation regulates circadian rhythmsbetaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosisSleep and circadian dysfunction in neurodegenerative disorders: insights from a mouse model of Huntington's diseaseThe Per2 negative feedback loop sets the period in the mammalian circadian clock mechanismRoles of protein ubiquitination and degradation kinetics in biological oscillationsDYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeepingCell type-specific functions of period genes revealed by novel adipocyte and hepatocyte circadian clock modelsLigand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner
P2860
Q21145708-A8FDFD8A-249E-4966-9BDA-7089F14BD1F3Q21563545-F0AEC871-1C46-43DB-9D14-7F10003AD567Q24296171-9F6A39FE-4A4E-44D2-BE55-27B43B5AA9E5Q24302471-6255DD12-C304-4680-A377-B4403E9E0EFFQ24304122-57DA6127-120D-4845-ADAA-D1019DCA5B23Q24306820-440E56D2-5ECA-4D9E-B9A6-C269A2E98286Q24309138-3C631DCD-5621-434E-8F80-42B50A292E75Q24321406-44B67982-F25A-4AA4-B0D1-6DCD1DBF0FACQ24336606-07363DC2-4F11-41E1-800F-F6A4F43844D4Q24599500-B50AA12A-B357-41CA-A9F6-2FB8D7422CBEQ24602881-E01A1C1B-9660-4BE3-B120-6A07DA210A61Q24629727-1BFBC8EF-45C6-406A-8CC9-FEFEE9F02ECEQ24646355-35E82BB9-DC7D-4C8E-9DBA-C1A418792FAAQ24648025-C0DFBCFD-725B-40A1-83F6-274D70E05229Q24654667-FF31B1E7-6853-4425-9E39-83C39890E852Q24655808-F3C4C060-20B6-4400-9EFD-3D855BF16A99Q26765492-F1EB9775-52E8-4205-9816-02A3E50802FFQ26774825-7F71D975-4EA9-457F-8A80-A8314632206FQ26782268-DD0F8213-D3D4-47AC-A24C-F01A6CBE6260Q27004052-A30A78FF-D508-4CCB-A01C-343F5CC112C2Q27318176-AB69C5FD-D1FB-4338-8979-A74046FF0B30Q27654626-2A91BB37-7EDA-4FC5-BB9F-3AD16F70CB9FQ27676853-5F2E962F-2A10-4131-95CD-8F352868059EQ27679392-DDA82402-A17B-42E9-ADD3-7F8FCF69FFF1Q27680111-00516700-3E31-478E-AFD9-41001FC127EBQ27687867-7AE02B4B-9B09-473B-8BFA-ECB5114FA45FQ28066015-4EBDED63-170B-4D0D-A475-FCD5EA704988Q28080676-299D3F03-5249-4643-ABDB-CF30F8FC5EF4Q28082125-8FC69755-DEC4-4C2C-8531-33DA0B9F7257Q28115944-F6F2F325-0B6F-48F0-9465-CCAE70AD1BBFQ28249506-3147B2E8-7049-4057-9B04-C168B7D74A55Q28273354-F5FAFD36-B510-452F-81E1-45BB4D25C52DQ28276789-81D26898-3200-46BF-AA72-612F9FE3AB9BQ28306984-EC558057-FC1D-4CAB-9771-90078E71F993Q28383062-6F95BE41-23B8-464C-A431-02799241C834Q28471808-6EEB1EB5-5DF7-4501-A5B1-9FC39EF9717AQ28482220-A30EC13E-008C-4452-9DF1-11A441AE9A60Q28512443-831D18CB-20E7-4C9A-9323-8A5022AF190DQ28541855-84521443-3E34-4603-AC7D-C0A912D06041Q28582355-12132E81-59E7-4617-9C40-2882A4EC9310
P2860
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@ast
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@en
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@nl
type
label
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@ast
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@en
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@nl
prefLabel
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@ast
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@en
SCFFbxl3 controls the oscillat ...... ation of cryptochrome proteins
@nl
P2093
P921
P3181
P356
P1433
P1476
SCFFbxl3 controls the oscillat ...... tion of cryptochrome proteins.
@en
P2093
Alessio Maiolica
Choogon Lee
Florian Bassermann
Giulio F Draetta
Luca Busino
Patrick M Nolan
Sofia I H Godinho
P3181
P356
10.1126/SCIENCE.1141194
P407
P577
2007-05-11T00:00:00Z