Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription

Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription

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http://www.wikidata.org/entity/Q24304994
Human cytomegalovirus infection causes premature and abnormal differentiation of human neural progenitor cellsCyclin-dependent kinase activity controls the onset of the HCMV lytic cycleCyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication.Inhibition of human cytomegalovirus immediate-early gene expression by cyclin A2-dependent kinase activityHuman cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.Alternative splicing of the human cytomegalovirus major immediate-early genes affects infectious-virus replication and control of cellular cyclin-dependent kinase.PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry.Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placentaSynthetic lethal mutations in the cyclin A interface of human cytomegalovirusTwo Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human CytomegalovirusRecruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription.Human cytomegalovirus riding the cell cycle.Downregulation of HMGA2 inhibits cellular proliferation and invasion, improves cellular apoptosis in prostate cancer.Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses.The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection
P2860

Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcription

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http://www.wikidata.org/entity/Q24304994
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2006 nî lūn-bûn
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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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type
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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prefLabel
Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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Repression of HMGA2 gene expre ...... tion of cyclin A transcription
@en-gb
Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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P1433
P1476
P2093
P2860
P304
P31
P356
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P433
P478
P50
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P698
P921
P932
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P1433
P1476
Repression of HMGA2 gene expre ...... tion of cyclin A transcription
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P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932