Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerDisruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndromeCentriole assembly and the role of Mps1: defensible or dispensable?Melatonin enhances DNA repair capacity possibly by affecting genes involved in DNA damage responsive pathwaysThe human microcephaly protein STIL interacts with CPAP and is required for procentriole formationHuman microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assemblyDeuterosome-mediated centriole biogenesisProduction of Basal Bodies in bulk for dense multicilia formationBuilding a ninefold symmetrical barrel: structural dissections of centriole assemblyThe Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole DuplicationCrystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephalyStructure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 KinasesMolecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesisThe PLK4-STIL-SAS-6 module at the core of centriole duplicationCentriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplicationMDM1 is a microtubule-binding protein that negatively regulates centriole duplicationTranscriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human diseaseSas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosomeThe Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesisCEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombinationCPAP is required for cilia formation in neuronal cells.Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression.Loss of centrioles causes chromosomal instability in vertebrate somatic cells.Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles.Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assemblyAsterless is required for centriole length control and sperm development53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.Epstein-Barr virus particles induce centrosome amplification and chromosomal instability.The origin of the second centriole in the zygote of Drosophila melanogasterPrecocious centriole disengagement and centrosome fragmentation induced by mitotic delayCell Cycle Regulation of the Centrosome and CiliumMulticilin drives centriole biogenesis via E2f proteinsSmall organelle, big responsibility: the role of centrosomes in development and disease.Centrobin-centrosomal protein 4.1-associated protein (CPAP) interaction promotes CPAP localization to the centrioles during centriole duplication.The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries.A molecular mechanism of mitotic centrosome assembly in DrosophilaDirect interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.Cep63 and cep152 cooperate to ensure centriole duplicationThe centrosome and its duplication cycleTwo Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability.
P2860
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P2860
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
description
2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@ast
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en-gb
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@nl
type
label
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@ast
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en-gb
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@nl
prefLabel
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@ast
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en-gb
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@nl
P2093
P2860
P921
P3181
P356
P1476
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
@en
P2093
Claude Antony
Florian Settele
Ingrid Hoffmann
Lena Ehret
Marc Arnold
Onur Cizmecioglu
Ramona Bahtz
Uta Haselmann-Weiss
P2860
P3181
P356
10.1083/JCB.201007107
P407
P577
2010-11-15T00:00:00Z