MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance
about
Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathyThe caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle.PTRF/Cavin-1 Deficiency Causes Cardiac Dysfunction Accompanied by Cardiomyocyte Hypertrophy and Cardiac FibrosisHSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytesCaveolin-1 knockout mice exhibit airway hyperreactivityCavin-3 dictates the balance between ERK and Akt signaling.The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes.MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors.SDPR induces membrane curvature and functions in the formation of caveolae.PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.Clathrin-independent pathways of endocytosis.Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation.Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance.Caveolae create local signalling domains through their distinct protein content, lipid profile and morphologyCells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.Cavin family proteins and the assembly of caveolae.FSHD myotubes with different phenotypes exhibit distinct proteomes.MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes.Caveolae and lipid trafficking in adipocytes.Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation.Caveolae, caveolins, cavins, and endothelial cell function: new insights.MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling.Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial FibrillationNew insights into the protein aggregation pathology in myotilinopathy by combined proteomic and immunolocalization analyses.Cavin4b/Murcb Is Required for Skeletal Muscle Development and Function in Zebrafish.Cardioprotective Role of Caveolae in Ischemia-Reperfusion Injury.Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulationDeletion of cavin genes reveals tissue-specific mechanisms for morphogenesis of endothelial caveolae.MURC deficiency in smooth muscle attenuates pulmonary hypertensionReduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillationDiagnosis and Therapy of Atrial Fibrillation: The Past, The Present and The Future.Molecular mechanisms of clathrin-independent endocytosis.Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolaeAtrial fibrillation: mechanisms, therapeutics, and future directions.Animal models for atrial fibrillation: clinical insights and scientific opportunities.Caveolae, caveolin, and cavins: potential targets for the treatment of cardiac disease.An introduction to murine models of atrial fibrillationContribution of small heat shock proteins to muscle development and function.Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-β in cardiac myocytes.
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P2860
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@ast
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en-gb
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@nl
type
label
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@ast
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en-gb
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@nl
prefLabel
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@ast
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en-gb
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@nl
P2093
P2860
P921
P3181
P356
P1476
MURC, a muscle-restricted coil ...... ion and conduction disturbance
@en
P2093
Hidemasa Oh
Hiroaki Matsubara
Koichiro Harada
Koji Isodono
Masashi Tagawa
Naofumi Takehara
Takehiro Ogata
Tetsuo Shioi
Tomomi Ueyama
Tomosaburo Takahashi
P2860
P304
P3181
P356
10.1128/MCB.02186-07
P407
P577
2008-05-01T00:00:00Z