The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
about
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesp73 as a pharmaceutical target for cancer therapyPhylogeny and function of the invertebrate p53 superfamilyDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Cancer models in Caenorhabditis elegans.Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.Roles of F-box proteins in cancerThe EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegansp73 in Cancer.Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factorsThe p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation.Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the NucleusDNA Copy Number Aberrations, and Human Papillomavirus Status in Penile Carcinoma. Clinico-Pathological Correlations and Potential Driver Genes.The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsRegulatory feedback loop between TP73 and TRIM32.Proteomic analysis of the NOS2 interactome in human airway epithelial cellsPirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiationIdentification of target genes for spermatogenic cell-specific KRAB transcription factor ZFP819 in a male germ cell line.p53-family proteins and their regulators: hubs and spokes in tumor suppression.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.p73-Binding Partners and Their Functional Significance.Tyr99 phosphorylation determines the regulatory milieu of tumor suppressor p73.Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survivalHigh throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagyPirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63.The Cul4A-DDB1 E3 ubiquitin ligase complex represses p73 transcriptional activity.Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and ΔNp73 isoforms through ubiquitin ligase PIR2.Rapamycin regulates biochemical metabolites.F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.Fbxo45 joins the 'Par-4'ty in controlling apoptosis of cancer cells.WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.
P2860
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P2860
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@ast
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en-gb
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@nl
type
label
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@ast
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en-gb
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@nl
prefLabel
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@ast
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en-gb
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@nl
P2093
P2860
P356
P1433
P1476
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2009.177
P407
P577
2009-09-03T00:00:00Z
P5875
P6179
1016858518