Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells
about
New developments in mast cell biologyDoc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanismVesicular trafficking and signaling for cytokine and chemokine secretion in mast cellsDistinct initial SNARE configurations underlying the diversity of exocytosisMunc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles.DOC2B, C2 domains, and calcium: A tale of intricate interactions.Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis.Granule cargo release from bone marrow-derived cells sustains cardiac hypertrophy.Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.Munc13-4*rab27 complex tethers secretory lysosomes at the plasma membrane.Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion.Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent mannerA network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.Munc18-2 and syntaxin 3 control distinct essential steps in mast cell degranulationCalcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis.Physiological function and molecular basis of STIM1-mediated calcium entry in immune cells.The mast cell: an evolutionary perspective.The SNARE Machinery in Mast Cell Secretion.Rab27 effectors, pleiotropic regulators in secretory pathways.The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story.Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37.Munc13-1 Translocates to the Plasma Membrane in a Doc2B- and Calcium-Dependent MannerMunc13 proteins control regulated exocytosis in mast cells.Release of TNF-α from macrophages is mediated by small GTPase Rab37.Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion
P2860
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P2860
Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells
description
2008 nî lūn-bûn
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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2008 թվականի ապրիլին հրատարակված գիտական հոդված
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
@zh-tw
2008年论文
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name
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@ast
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en-gb
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@nl
type
label
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@ast
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en-gb
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@nl
prefLabel
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@ast
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en-gb
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@nl
P2093
P921
P1476
Doc2 alpha and Munc13-4 regula ...... osome exocytosis in mast cells
@en
P2093
Ayuko Sakane
Hironori Higashio
Hiroyoshi Ishizaki
Jun Miyoshi
Noriyuki Nishimura
Satoshi Orita
Takuya Sasaki
P304
P356
10.4049/JIMMUNOL.180.7.4774
P407
P577
2008-04-01T00:00:00Z