Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
about
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsGenome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complexLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionCamptothecin-induced downregulation of MLL5 contributes to the activation of tumor suppressor p53A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcriptionIdentification and characterization of the human Set1B histone H3-Lys4 methyltransferase complexPRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylationA phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complexCoactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferasesThe tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factorsIdentification of the MLL2 complex as a coactivator for estrogen receptor alphaMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDHuman ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding proteinMolecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASSA role of histone H3 lysine 4 methyltransferase components in endosomal traffickingKnockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsOn the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complexThe tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.The parafibromin tumor suppressor protein is part of a human Paf1 complexInherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversiesTranscription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interferenceFamilial syndromes associated with neuroendocrine tumoursHijacked in cancer: the KMT2 (MLL) family of methyltransferasesA role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ lineCrystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinThe plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferasesThe same pocket in menin binds both MLL and JUND but has opposite effects on transcriptionStructural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone MethyltransferasesThe super elongation complex (SEC) and MLL in development and disease.Targeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesSet1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory.Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation.The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) PhenotypeMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsX-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesGrowth hormone-secreting tumors: genetic aspects and data from animal modelsMultiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)
P2860
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P248
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P2860
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@ast
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en-gb
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@nl
type
label
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@ast
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en-gb
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@nl
prefLabel
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@ast
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en-gb
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@nl
P2093
P50
P921
P3181
P1433
P1476
Menin associates with a tritho ...... mplex and with the hoxc8 locus
@en
P2093
Arindam Bhattacharjee
Christina M Hughes
Christine A Biondi
D Neil Hayes
Graham F Kay
Jay L Hess
Jeffrey C Lee
Kalai Selvi Shanmugam
Nicholas K Hayward
Terry D Copeland
P304
P3181
P356
10.1016/S1097-2765(04)00081-4
P407
P577
2004-02-27T00:00:00Z