Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent
about
The retinal determination gene network: from developmental regulator to cancer therapeutic targetMultiple Functions of the Eya Phosphotyrosine PhosphataseProtein and DNA modifications: evolutionary imprints of bacterial biochemical diversification and geochemistry on the provenance of eukaryotic epigeneticsCrystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factorDual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1The X-ray crystallographic structure and specificity profile of HAD superfamily phosphohydrolase BT1666: Comparison of paralogous functions inB. thetaiotaomicronThe DNA Damage Response: Making It Safe to Play with KnivesThe EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromaroneStructure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agentsAllosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.Histone variants: emerging players in cancer biology.The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration, and invasion of tumor cellsA phosphotyrosine switch determines the antitumor activity of ERβ.Methylated eyes absent 4 (EYA4) gene promotor in non-neoplastic mucosa of ulcerative colitis patients with colorectal cancer: evidence for a field effectStructure and catalytic mechanism of human protein tyrosine phosphatome.Phosphatases in the cellular response to DNA damage.Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.DNA double-strand break signaling and human disorders.Targeting protein tyrosine phosphatases for anticancer drug discovery.A comprehensive view of the epigenetic landscape. Part II: Histone post-translational modification, nucleosome level, and chromatin regulation by ncRNAs.The SIX1-EYA transcriptional complex as a therapeutic target in cancer.Histone modifiers in cancer: friends or foes?Histones: at the crossroads of peptide and protein chemistry.Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.BAZ1B is dispensable for H2AX phosphorylation on Tyrosine 142 during spermatogenesisHistone H2A variants in nucleosomes and chromatin: more or less stable?The Eyes Absent proteins in development and disease.The Eyes Absent Proteins in Developmental and Pathological Angiogenesis.Co-mutation of histone H2AX S139A with Y142A rescues Y142A-induced ionising radiation sensitivity.Retinal Axon Guidance Requires Integration of Eya and the Jak/Stat Pathway into Phosphotyrosine-Based Signaling Circuitries in DrosophilaEYA4 gene functions as a prognostic marker and inhibits the growth of intrahepatic cholangiocarcinoma.Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.Markers of fitness in a successful enzyme superfamily.Protein tyrosine phosphatases in glioma biologyHistone tyrosine phosphorylation comes of age.WSTF does it all: a multifunctional protein in transcription, repair, and replication.The dynamic interplay in chromatin remodeling factors polycomb and trithorax proteins in response to DNA damage.Human HAD phosphatases: structure, mechanism, and roles in health and disease.The EYA-SO/SIX complex in development and disease.
P2860
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P2860
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@ast
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en-gb
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@nl
type
label
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@ast
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en-gb
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@nl
prefLabel
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@ast
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en-gb
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@nl
P2093
P2860
P921
P3181
P356
P1476
Dephosphorylation of the C-ter ...... rotein phosphatase eyes absent
@en
P2093
Andrew Xiao
C David Allis
Dae Gwin Jeong
Navasona Krishnan
Nicholas K Tonks
Seong Eon Ryu
Seung Jun Kim
Suk-Kyeong Jung
P2860
P304
P3181
P356
10.1074/JBC.C900032200
P407
P577
2009-06-12T00:00:00Z