SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development
about
Identification of candidate genes for human pituitary development by EST analysisARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomaliesComplex architecture and regulated expression of the Sox2ot locus during vertebrate developmentPleiotropic functions for transcription factor zscan10.Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Spectrum of clinical presentations and endocrinological findings of patients with septo-optic dysplasia: a retrospective study.Mutations in Human Accelerated Regions Disrupt Cognition and Social BehaviorDiscovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches.Direct transcriptional regulation of Six6 is controlled by SoxB1 binding to a remote forebrain enhancerGenetic regulation of pituitary gland development in human and mouseThe HMG-box transcription factor Sox4b is required for pituitary expression of gata2a and specification of thyrotrope and gonadotrope cells in zebrafish.Examination of SOX2 in variable ocular conditions identifies a recurrent deletion in microphthalmia and lack of mutations in other phenotypesThe use of neuroimaging for assessing disorders of pituitary development.The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration.Septo-optic dysplasiaActivation of Sox3 gene by thyroid hormone in the developing adult intestinal stem cell during Xenopus metamorphosisIsolated hypogonadotropic hypogonadism with SOX2 mutation and anophthalmia/microphthalmia in offspringKnockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heartRMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development.The Sox transcriptional factors: Functions during intestinal development in vertebrates.SOX2 regulates the hypothalamic-pituitary axis at multiple levelsSystematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control.SOX2 haploinsufficiency is associated with slow progressing hypothalamo-pituitary tumours.Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors.SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitaryStem/progenitor cells in the developing human cerebellum: an immunohistochemical study.Septo-optic dysplasia complex: Clinical and radiological manifestations in Omani children.The molecular basis of hypopituitarismClinical and mutation analysis of 51 probands with anophthalmia and/or severe microphthalmia from a single center.Induced pluripotent stem cells: fundamentals and applications of the reprogramming process and its ramifications on regenerative medicine.Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation.Genetics of Combined Pituitary Hormone Deficiency: Roadmap into the Genome Era.Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancersSpontaneous evolution of an unusual cortical malformation in SOX2 anophthalmia syndrome.A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina.Mutation spectrum and phenotypic variation in nine patients with SOX2 abnormalities.SOX2 anophthalmia syndrome in adulthood - a neurodegenerative picture?Human accelerated regions and other human-specific sequence variations in the context of evolution and their relevance for brain development.Comparative expression patterns of Sox2 and Sox19 genes in the forebrain of developing and adult turbot (Scophthalmus maximus).De novo microdeletions and point mutations affecting SOX2 in three individuals with intellectual disability but without major eye malformations.
P2860
Q21283769-ACE32C92-E033-43B1-B6C6-5F6358C9C514Q24324164-9D053BD3-2094-4B1E-8836-3B7EA2472D3CQ24651231-136B4F92-8926-4A51-9E40-B9C4A56A05B4Q30433100-6E956F66-8648-495A-A639-D1DF351638AAQ30494084-E31F36DD-4E32-4B2B-B24A-57372A66FC72Q30933908-1C2F2794-06EB-46CE-A1DD-112F5D615C6AQ33268604-DBE0DE23-168A-44C9-AF14-DEA96495A4A5Q33397184-3CD2B148-9701-4A4F-BCD0-D9D716FCDD93Q33563970-8709D5B9-7529-4F87-B2F7-E54B6ED790BAQ33590141-059BAD22-1029-4A41-BC50-346F4CEC5BDAQ33636387-A06AD271-FCC1-40F7-B19F-CEEA6DF9FB08Q33821133-8306ABF8-6D18-4559-8B25-6A3216421D77Q34033813-C4CF17B7-20EB-4EA5-807F-8C1403D961CFQ34159882-78C70A90-4AC9-4E56-9B3D-B0D087A5FD71Q34328853-4A344525-DCB5-4D74-9CE0-81F864395893Q34551733-336C23A7-CC83-4B46-8103-E9E66A2FFEEBQ35108596-BB2F2645-E469-4C0A-B5A2-04570B90F13BQ35176657-AC8D3722-ECA1-4E05-B499-7B7ABAC5C942Q35582378-F99AB90F-241C-43A1-8B77-2671509EEE37Q36115146-3856AB84-5ADD-4756-B4A8-7476A65181BDQ36290332-F54ECA35-BE6C-47E7-BF78-DCA2CA6A1C39Q36354907-E9EF9056-7951-4E17-9237-2B467E8388A2Q36365816-6F80027C-88A9-479C-AF27-171837987FF1Q36948830-080A38ED-837D-4EC3-B07F-1E15C3F88671Q37120477-29739282-A188-4E4F-8847-FF9F78F3B153Q37336266-42CE9278-E605-44A2-AFAB-03D979E4A28AQ37413710-FE87DFFB-98D5-41DA-A9A5-09E702D21AD7Q37456706-1990000F-4B45-4323-8DD7-C9BD37991AD5Q37483886-688EDEFB-0767-43D0-8997-76E09A0EA6F0Q37889165-87DA3F57-13F4-4BE5-8CEE-3A4F996BDE55Q38272073-9BF27B59-FA40-4F9E-93B8-E05F13A928A8Q38797075-742DEC0A-29CC-4320-920C-E9E203BA9A5CQ39365719-A9A900E1-13A9-4D9D-9226-3BEC3EAC1455Q41811392-AA2744E7-CC94-4F54-A94B-7610166A6A97Q42548145-D8B7FD4C-503A-4A98-AD0D-5259B5910E44Q45343810-AB078944-03B3-41CB-82DA-FD5328923D52Q46124948-FE3509E9-AB87-45A8-86CB-AD4AD20E524BQ46259543-16279690-B2D1-42E6-829A-BF71A7708CFAQ47180115-29DA973B-3C9C-4310-8730-A5042E0AFC38Q52113860-B235618E-D525-41B3-B799-03CF35259345
P2860
SOX2 plays a critical role in the pituitary, forebrain, and eye during human embryonic development
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
SOX2 plays a critical role in ...... ng human embryonic development
@ast
SOX2 plays a critical role in ...... ng human embryonic development
@en
SOX2 plays a critical role in ...... ng human embryonic development
@en-gb
SOX2 plays a critical role in ...... ng human embryonic development
@nl
type
label
SOX2 plays a critical role in ...... ng human embryonic development
@ast
SOX2 plays a critical role in ...... ng human embryonic development
@en
SOX2 plays a critical role in ...... ng human embryonic development
@en-gb
SOX2 plays a critical role in ...... ng human embryonic development
@nl
prefLabel
SOX2 plays a critical role in ...... ng human embryonic development
@ast
SOX2 plays a critical role in ...... ng human embryonic development
@en
SOX2 plays a critical role in ...... ng human embryonic development
@en-gb
SOX2 plays a critical role in ...... ng human embryonic development
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
SOX2 plays a critical role in ...... ng human embryonic development
@en
P2093
Daniel Kelberman
David Taylor
Dianne Gerrelli
Iain C A F Robinson
John A Crolla
John W Gregory
Mehul T Dattani
Rita Fischetto
Robin Lovell-Badge
Rodger Palmer
P2860
P304
P3181
P356
10.1210/JC.2007-2337
P407
P577
2008-05-01T00:00:00Z