ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
about
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) familyADAMTS-12 metalloprotease is necessary for normal inflammatory responseNegative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiationInhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulinThe Function and Roles of ADAMTS-7 in Inflammatory DiseasesThe metalloproteinase ADAMTS1: a comprehensive review of its role in tumorigenic and metastatic pathways.Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferationADAMTS-12: a multifaced metalloproteinase in arthritis and inflammationThe t(14,15) in mouse strain CBA/CaH-T(14;15)6Ca/J causes a break in the ADAMTS12 geneADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.Novel cartilage oligomeric matrix protein (COMP) neoepitopes identified in synovial fluids from patients with joint diseases using affinity chromatography and mass spectrometry.Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix proteinADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis.ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis.The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.The thrombospondins.Progranulin: a growth factor, a novel TNFR ligand and a drug targetWnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis.Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA.Glucosamine Downregulates the IL-1β-Induced Expression of Proinflammatory Cytokine Genes in Human Synovial MH7A Cells by O-GlcNAc Modification-Dependent and -Independent Mechanisms.Cartilage oligomeric matrix protein specific antibodies are pathogenicEmerging Roles of ADAMTSs in Angiogenesis and Cancer.Elucidating the function of non catalytic domains of collagenases and aggrecanases.ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases.The role of ADAMTSs in arthritisα-2-Macroglobulin: a physiological guardian.Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix.c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic CellsCharacterization and regulation of ADAMTS-16.Integrin alpha(7)beta(1) COMPels smooth muscle cells to maintain their quiescence.Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent.Co-segregation of Freiberg's infraction with a familial translocation t(5;7)(p13.3;p22.2) ascertained by a child with cri du chat syndrome and brachydactyly type A1B.The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.Cartilage Oligomeric Matrix Protein Level in Rheumatic Diseases: Potential Use as a Marker for Measuring Articular Cartilage Damage and/or the Therapeutic Efficacy of Treatments
P2860
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P2860
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@ast
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en-gb
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@nl
type
label
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@ast
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en-gb
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@nl
prefLabel
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@ast
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en-gb
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@nl
P2093
P2860
P921
P3181
P356
P1476
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
@en
P2093
Bantoo Sehgal
Chuan-ju Liu
Kiril Ilalov
Paul E Di Cesare
Ronald D Howell
P2860
P304
P3181
P356
10.1074/JBC.M513433200
P407
P577
2006-06-09T00:00:00Z