Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia
about
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia geneProtein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein familyNew insight into the molecular mechanisms of MLL-associated leukemiaThe leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusionsIdentification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 geneDetection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitorsRegulation of αENaC transcriptionFunctional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding proteinENL, the MLL fusion partner in t(11;19), binds to the c-Abl interactor protein 1 (ABI1) that is fused to MLL in t(10;11)+.Characterization and potential function of a novel testis-specific nucleoporin BS-63.Construction of a high-resolution 2.5-Mb transcript map of the human 6p21.2-6p21.3 region immediately centromeric of the major histocompatibility complex.Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia.Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos.The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomInvolvement of the ALL-1 gene in a solid tumor.FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23).Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains.Widely expressed Af17 is likely not required for embryogenesis, hematopoiesis, and animal survival.Developmental analysis and subcellular localization of the murine homologue of ELL.Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesisCancer genetics of epigenetic genes.RNAi screens in mice identify physiological regulators of oncogenic growthAF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha.Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival.The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice.Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction.Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.Molecular analysis of infant acute leukemia.Molecular analysis of more than 140 gene fusion variants and aberrant activation of EVI1 and TLX1 in hematological malignancies.Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia.Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia.The human LASP1 gene is fused to MLL in an acute myeloid leukemia with t(11;17)(q23;q21).SEPT2 is a new fusion partner of MLL in acute myeloid leukemia with t(2;11)(q37;q23).Acute myeloid leukemiaAcute Myeloid Leukemia
P2860
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P2860
Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia
description
1994 nî lūn-bûn
@nan
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@ast
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en-gb
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@nl
type
label
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@ast
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en-gb
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@nl
prefLabel
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@ast
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en-gb
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@nl
P2093
P2860
P921
P356
P1476
Leucine-zipper dimerization mo ...... ALL-1 (MLL) in acute leukemia
@en
P2093
D Leshkowitz
T Nakamura
P2860
P304
P356
10.1073/PNAS.91.17.8107
P407
P577
1994-08-16T00:00:00Z