Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
about
N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexCharacterization of E3Histone, a novel testis ubiquitin protein ligase which ubiquitinates histones.An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesisNedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaSmad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNTsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag)Iodine alters gene expression in the MCF7 breast cancer cell line: evidence for an anti-estrogen effect of iodineCdc20 associates with the kinase aurora2/AikEarly mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progressionExpression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinomaCyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphaseFunctional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteinsIdentification of genes involved in Ca2+ ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndromeK11-linked ubiquitin chains as novel regulators of cell divisionStructural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosisTSG101 may be the prototype of a class of dominant negative ubiquitin regulatorsUSP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesisThe anaphase promoting complex/cyclosome: a machine designed to destroyCell cycle-regulated proteolysis of mitotic target proteins.Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer.Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis.Nucleoporin levels regulate cell cycle progression and phase-specific gene expressionInterleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment.Identification and validation of genes involved in cervical tumourigenesis.From rabbit reticulocytes to clam oocytes: in search of the system that targets mitotic cyclins for degradationUbiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic ratsQuantitative proteomics identify novel miR-155 target proteins.Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarraysCompromised spindle assembly checkpoint due to altered expression of Ubch10 and Cdc20 in human papillomavirus type 16 E6- and E7-expressing keratinocytesOverexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin.UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer.High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression.Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma.Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin.Interpreting the molecular biology and clinical behavior of multiple myeloma in the context of global gene expression profiling.Knockdown of UbcH10 enhances the chemosensitivity of dual drug resistant breast cancer cells to epirubicin and docetaxel.Maternal Wnt/STOP signaling promotes cell division during early Xenopus embryogenesis
P2860
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P2860
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@ast
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en-gb
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@nl
type
label
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@ast
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en-gb
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@nl
prefLabel
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@ast
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en-gb
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@nl
P2093
P2860
P356
P1476
Dominant-negative cyclin-selec ...... cH10 blocks cells in metaphase
@en
P2093
A Aristarkhov
F M Townsley
J V Ruderman
P2860
P304
P356
10.1073/PNAS.94.6.2362
P407
P577
1997-03-18T00:00:00Z