Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
about
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axonsEnzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersNMNAT1 mutations cause Leber congenital amaurosisNutrient-sensitive mitochondrial NAD+ levels dictate cell survivalNuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?The power to reduce: pyridine nucleotides--small molecules with a multitude of functionsRegulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersNew strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncologyDiabetic complications within the context of aging: Nicotinamide adenine dinucleotide redox, insulin C-peptide, sirtuin 1-liver kinase B1-adenosine monophosphate-activated protein kinase positive feedback and forkhead box O3Neuronal endoplasmic reticulum stress in axon injury and neurodegenerationOxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cellsThe Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat proteinBifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD MetabolismTargeting NAD Biosynthesis in Bacterial Pathogens: Structure-Based Development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadDComplexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and ImprovementMutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophyDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingMitochondrial health, the epigenome and healthspanSIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycleExpression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria.Axon degeneration: Molecular mechanisms of a self-destruction pathwayMammalian sirtuins: biological insights and disease relevanceA rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degenerationAnalysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyteNAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity.Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Overexpression of Wld(S) or Nmnat2 in mauthner cells by single-cell electroporation delays axon degeneration in live zebrafish.Novel compound heterozygous NMNAT1 variants associated with Leber congenital amaurosis.Proteomic Analysis between U87MG and U343MG-A Cell Lines: Searching for Candidate Proteins for Glioma Invasion.Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortexThe secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis.Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferasesRole of NAD+ and mitochondrial sirtuins in cardiac and renal diseasesNew facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.Wallerian degeneration, wld(s), and nmnat.Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes
P2860
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P248
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P2860
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@ast
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en-gb
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@nl
type
label
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@ast
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en-gb
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@nl
prefLabel
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@ast
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en-gb
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@nl
P2860
P50
P921
P3181
P356
P1476
Subcellular compartmentation a ...... e adenylyltransferase isoforms
@en
P2093
Felicitas Berger
P2860
P304
36334-36341
P3181
P356
10.1074/JBC.M508660200
P407
P577
2005-08-23T00:00:00Z