Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP - Wikidata - thesis-toulmin - TriplyDB

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

http://www.wikidata.org/entity/Q24318478

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The WASP and WAVE family proteins The essential role of profilin in the assembly of actin for microspike formation.WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac The small GTPase RalA targets filamin to induce filopodia Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts Pleckstrin induces cytoskeletal reorganization via a Rac-dependent pathway Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation SPECs, small binding proteins for Cdc42 A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin Borg proteins control septin organization and are negatively regulated by Cdc42 Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling WASH and the Arp2/3 complex regulate endosome shape and trafficking.Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin Identification of splicing variants of Rapostlin, a novel RND2 effector that interacts with neural Wiskott-Aldrich syndrome protein and induces neurite branching Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination The Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamics Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1 Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri A WASp-VASP complex regulates actin polymerization at the plasma membrane.Motility determinants in WASP family proteins.Actin-based motility of intracellular microbial pathogens Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42 Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages Syndapin isoforms participate in receptor-mediated endocytosis and actin organization A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42 Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.The Wiskott-Aldrich syndrome Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility Functions and regulation of circular dorsal ruffles GTP hydrolysis of TC10 promotes neurite outgrowth through exocytic fusion of Rab11- and L1-containing vesicles by releasing exocyst component Exo70

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

http://www.wikidata.org/entity/Q24318478

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունվարին հրատարակված գիտական հոդված

@hy

1998年の論文

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1998年論文

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1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@ast

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en-gb

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@nl

type

label

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@ast

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en-gb

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@nl

prefLabel

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@ast

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@en-gb

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

@nl

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

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H Miki

http://www.w3.org/2001/XMLSchema#string

T Sasaki

http://www.w3.org/2001/XMLSchema#string

T Takenawa

http://www.w3.org/2001/XMLSchema#string

Y Takai

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P2860

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Identification of N-WASP homologs in human and rat brain

The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts

How profilin promotes actin filament assembly in the presence of thymosin beta 4.

Identification, characterization, and intracellular distribution of cofilin in Dictyostelium discoideum.

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade.

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93-6

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scholarly article

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3102897

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10.1038/34208

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6662

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P478

391

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1014134258

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P698

9422512

http://www.w3.org/2001/XMLSchema#string

P921

WASP like actin nucleation promoting factor

macromolecular complex assembly