Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease
about
Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phoxAssembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targetsCytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox)156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phoxDeletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activityHematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (second update)Activation and assembly of the NADPH oxidase: a structural perspectiveTumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscleThe adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase.Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phoxSH3-dependent assembly of the phagocyte NADPH oxidase.Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.Probing the role of the carboxyl terminus of the gp91phox subunit of neutrophil flavocytochrome b558 using site-directed mutagenesis.The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophilsNOX enzymes and pulmonary disease.Benchmarking B-cell epitope prediction for the design of peptide-based vaccines: problems and prospects.Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558.Extensive natural variation for cellular hydrogen peroxide release is genetically controlled.Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phoxMacrophage NADPH oxidase flavocytochrome B localizes to the plasma membrane and Rab11-positive recycling endosomesLocation of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox.Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA.NADPH-cytochrome c reductase from human neutrophil membranes: purification, characterization and localizationDirect involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.The enigmatic cytochrome b-559 of oxygenic photosynthesis.The NADPH oxidase of phagocytic leukocytes.NOX2 generates superoxide from oxygen
P2860
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P2860
Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Point mutation in the cytoplas ...... chronic granulomatous disease
@ast
Point mutation in the cytoplas ...... chronic granulomatous disease
@en
Point mutation in the cytoplas ...... chronic granulomatous disease
@en-gb
Point mutation in the cytoplas ...... chronic granulomatous disease
@nl
type
label
Point mutation in the cytoplas ...... chronic granulomatous disease
@ast
Point mutation in the cytoplas ...... chronic granulomatous disease
@en
Point mutation in the cytoplas ...... chronic granulomatous disease
@en-gb
Point mutation in the cytoplas ...... chronic granulomatous disease
@nl
prefLabel
Point mutation in the cytoplas ...... chronic granulomatous disease
@ast
Point mutation in the cytoplas ...... chronic granulomatous disease
@en
Point mutation in the cytoplas ...... chronic granulomatous disease
@en-gb
Point mutation in the cytoplas ...... chronic granulomatous disease
@nl
P2093
P2860
P356
P1476
Point mutation in the cytoplas ...... chronic granulomatous disease
@en
P2093
E A Pierce
J T Curnutte
M C Dinauer
R W Erickson
T J Muhlebach
P2860
P304
P356
10.1073/PNAS.88.24.11231
P407
P577
1991-12-15T00:00:00Z