Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
about
Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicityBCoR, a novel corepressor involved in BCL-6 repressionAtrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcriptionCharacterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independentlyShort GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophyThe ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1NRP/B, a novel nuclear matrix protein, associates with p110(RB) and is involved in neuronal differentiationAtaxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptorsViral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruptionBoat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.Short-sequence DNA repeats in prokaryotic genomesEvi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene productThe interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn)Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseasesModulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signalingThe localization and interactions of huntingtinThe nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activityNopp140 functions as a molecular link between the nucleolus and the coiled bodiesPML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteinsThe ER repeat protein YT521-B localizes to a novel subnuclear compartmentMutant Rab24 GTPase is targeted to nuclear inclusions.Mouse models of polyglutamine diseases: review and data table. Part IPolyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation.The structure of the AXH domain of spinocerebellar ataxin-1Expansion, mosaicism and interruption: mechanisms of the CAG repeat mutation in spinocerebellar ataxia type 1Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtinSynaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific proteaseNeurodegenerative disease: neuron protection agencyAltered trafficking of membrane proteins in purkinje cells of SCA1 transgenic miceHAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic miceThe cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicityA Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in micePondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Nuclear aggresomes form by fusion of PML-associated aggregates.Localization and importance of the adenovirus E4orf4 protein during lytic infectionInsoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cellsPuromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear inclusions enriched with HSP70 and Proteasomes.
P2860
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P2860
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@ast
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en-gb
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@nl
type
label
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@ast
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en-gb
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@nl
prefLabel
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@ast
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en-gb
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@nl
P2093
P2860
P3181
P356
P1433
P1476
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
@en
P2093
A Servadio
C J Cummings
I A Klement
P J Skinner
P2860
P2888
P3181
P356
10.1038/40153
P407
P577
1997-10-30T00:00:00Z
P5875
P6179
1048794276