Mutations in the hminK gene cause long QT syndrome and suppress IKs function
about
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesisCloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structureKCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channelAnalysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunitsO-glycosylation of the cardiac I(Ks) complexRegulation of the Kv2.1 potassium channel by MinK and MiRP1Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsyOestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epitheliumIntracellular domains interactions and gated motions of I(KS) potassium channel subunitsKCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.Ectopic expression of KCNE3 accelerates cardiac repolarization and abbreviates the QT intervalSpectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic testKCNE4 is an inhibitory subunit to the KCNQ1 channelKCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channelEpidemiology of sudden cardiac death: clinical and research implicationsGenetics of inherited primary arrhythmia disordersNeuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and PitfallsMolecular and genetic basis of sudden cardiac deathIon Channels in the HeartCaMKII regulation of cardiac K channelsGene regulatory networks in cardiac conduction system developmentStructure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel † ‡Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathIdentification of a Kir3.4 mutation in congenital long QT syndromeA common polymorphism associated with antibiotic-induced cardiac arrhythmiaExpression and coassociation of ERG1, KCNQ1, and KCNE1 potassium channel proteins in horse heartFunctional significance of K+ channel β-subunit KCNE3 in auditory neuronsKCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channelPreparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndromeFunctional delivery of a membrane protein into oocyte membranes using bicellesDisruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transportIKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunitsEndogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studiesAn LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardiaCorrection of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effectsElectrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1AMIGO is an auxiliary subunit of the Kv2.1 potassium channelMiRP3 acts as an accessory subunit with the BK potassium channelTargeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice.Congenital Long QT Syndrome: An Update and Present Perspective in Saudi Arabia.
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P2860
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@ast
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en-gb
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@nl
type
label
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@ast
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en-gb
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@nl
prefLabel
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@ast
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en-gb
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
@en
P2093
I Splawski
M C Sanguinetti
M H Lehmann
M T Keating
M Tristani-Firouzi
P2860
P2888
P304
P3181
P356
10.1038/NG1197-338
P407
P577
1997-11-01T00:00:00Z
P6179
1014348732