Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain
about
A family of cAMP-binding proteins that directly activate Rap1Two pacemaker channels from human heart with profoundly different activation kineticsTetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channelsPacemaker channel dysfunction in a patient with sinus node diseaseHypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channelsMolecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testisFrom damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotesHCN channels and heart rateCortical HCN channels: function, trafficking and plasticityMolecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channelEnhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampusDifferent roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channelsA novel WD repeat protein component of the methylosome binds Sm proteinsTemperature affects voltage-sensitive conductances differentially in octopus cells of the mammalian cochlear nucleusRegulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regionsDifferential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampusProperties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotideC-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gatingGene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodelingElevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillationsPostnatal development of dendritic synaptic integration in rat neocortical pyramidal neuronsCalcium-dependent binding of HCN1 channel protein to hair cell stereociliary tip link protein protocadherin 15 CD3HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminalsColocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cellsThe murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotidesAbsence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methodsExpression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart developmentAncient gene transfer from algae to animals: mechanisms and evolutionary significanceStructures of the Human HCN1 Hyperpolarization-Activated ChannelExploring Human Diseases and Biological Mechanisms by Protein Structure Prediction and Modeling.HCN channels expressed in the inner ear are necessary for normal balance function.The magnitudes of hyperpolarization-activated and low-voltage-activated potassium currents co-vary in neurons of the ventral cochlear nucleus.Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2Distinct expression patterns of HCN channels in HL-1 cardiomyocytes.Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes.The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster.Molecular characterization, functional expression, and developmental profile of an ether à-go-go K+ channel in the tobacco hornworm Manduca sexta.A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.
P2860
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P2860
Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Identification of a gene encod ...... ted pacemaker channel of brain
@ast
Identification of a gene encod ...... ted pacemaker channel of brain
@en
Identification of a gene encod ...... ted pacemaker channel of brain
@en-gb
Identification of a gene encod ...... ted pacemaker channel of brain
@nl
type
label
Identification of a gene encod ...... ted pacemaker channel of brain
@ast
Identification of a gene encod ...... ted pacemaker channel of brain
@en
Identification of a gene encod ...... ted pacemaker channel of brain
@en-gb
Identification of a gene encod ...... ted pacemaker channel of brain
@nl
prefLabel
Identification of a gene encod ...... ted pacemaker channel of brain
@ast
Identification of a gene encod ...... ted pacemaker channel of brain
@en
Identification of a gene encod ...... ted pacemaker channel of brain
@en-gb
Identification of a gene encod ...... ted pacemaker channel of brain
@nl
P2093
P3181
P1433
P1476
Identification of a gene encod ...... ted pacemaker channel of brain
@en
P2093
E R Kandel
S A Siegelbaum
P304
P3181
P356
10.1016/S0092-8674(00)81434-8
P407
P577
1998-05-29T00:00:00Z